在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CERS3 Antibody

  • 中文名稱:
    CERS3兔多克隆抗體
  • 貨號(hào):
    CSB-PA142124
  • 規(guī)格:
    ¥1100
  • 圖片:
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: TM4 cells, Primary antibody: CSB-PA142124(CERS3 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    CERS3
  • 別名:
    CERS3; LASS3; Ceramide synthase 3; CerS3; Dihydroceramide synthase 3; LAG1 longevity assurance homolog 3; Sphingosine N-acyltransferase CERS3; Ultra-long-chain ceramide synthase CERS3; Very-long-chain ceramide synthase CERS3
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Synthetic peptide of Human CERS3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward very- and ultra-long-chain fatty acyl-CoA (chain length greater than C22). N-acylates sphinganine and sphingosine bases to form dihydroceramides and ceramides in de novo synthesis and salvage pathways, respectively. It is crucial for the synthesis of ultra-long-chain ceramides in the epidermis, to maintain epidermal lipid homeostasis and terminal differentiation.
  • 基因功能參考文獻(xiàn):
    1. Novel mutations in CERS3 co-segregated with the ichthyosis phenotype in six Iranian families. PMID: 28875980
    2. testis-specific SLs, which we also link to CerS3 in human testis, are quintessential for male fertility. PMID: 26045466
    3. Our findings demonstrate that synthesis of very long chain ceramides by CerS3 is a crucial early step for the skin barrier formation and link disorders presenting with congenital ichthyosis to defects in sphingolipid metabolism and lipid architecture. PMID: 23549421
    4. these data present a novel pathway involved in ARCI development and, moreover, provide the first evidence that CERS3 plays an essential role in human sphingolipid metabolism for the maintenance of epidermal lipid homeostasis. PMID: 23754960
  • 相關(guān)疾?。?/div>
    Ichthyosis, congenital, autosomal recessive 9 (ARCI9)
  • 亞細(xì)胞定位:
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 組織特異性:
    Expressed in the epidermis, where it localizes at the interface between the stratum granulosum and the stratum corneum (at protein level).
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 23752

    OMIM: 615023

    KEGG: hsa:204219

    STRING: 9606.ENSP00000284382

    UniGene: Hs.662371



主站蜘蛛池模板: 蜜臀性色av免费| 香港台湾经典三级a视频| 国产精品老汉av| 熟女chachacha性少妇| 一本一本久久a久久精品综合麻豆| 日韩人妻无码一区二区三区| 无码人妻久久一区二区三区| 精品国产你懂的在线观看 | 公与淑婷厨房猛烈进出视频免费| 亚洲毛片αv无线播放一区| 日韩无码电影| 国产国产久热这里只有精品| 久久久婷婷五月亚洲97色| 精品久久久无码中文字幕| 国产日韩精品一区二区三区在线| 欧美性色黄大片www喷水| 在线观看精品视频网站| 日本人妻巨大乳挤奶水| 黑人巨茎大战俄罗斯美女| 欧洲 亚洲 国产图片综合| 久久国产高潮流白浆免费观看| 男人扒开女人腿桶到爽免费| 快好爽射给我视频| 日日摸夜夜摸狠狠摸婷婷| 欧美自拍另类欧美综合图片区| 亚洲精品国产精品国自产观看| 国产熟女亚洲精品麻豆| 亚洲a∨精品无码一区二区| 天堂а√在线中文在线最新版| 久久久婷婷五月亚洲97号色| 欧美肥婆性猛交xxxx| 精品一品国产午夜福利视频| 激情内射日本一区二区三区| 亚洲精品国产嫩草在线观看东京热| 美女扒开腿让男人桶爽揉| 66lu国产在线观看| 老湿机69福利区无码| 日日天日日夜日日摸| 久久99国产精品久久99| 成人欧美一区二区三区1314| 午夜福利啪啪无遮挡免费|