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CEP83 Antibody

  • 中文名稱：
    CEP83兔多克隆抗體
  • 貨號：
    CSB-PA896730ESR1HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: CEP83 antibody at 2.41 μg/ml + Raji whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 83, 68 kDa
      Observed band size: 83, 55 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA896730ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA896730ESR1HU at dilution of 1:100
    • Immunofluorescent analysis of PC-3 cells using CSB-PA896730ESR1HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) CEP83 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CEP83
  • 別名：
    CEP83 antibody; CCDC41Centrosomal protein of 83 kDa antibody; Cep83 antibody; Coiled-coil domain-containing protein 41 antibody; Renal carcinoma antigen NY-REN-58 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Centrosomal protein of 83 kDa protein (34-260AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the distal appendage region of the centriole involved in the initiation of primary cilium assembly. May collaborate with IFT20 in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium during the initiation of primary cilium assembly.
  • 基因功能參考文獻：
    1. We have identified mutations in CEP83, another distal appendages component encoding gene, as a cause of infantile nephronophthisis associated with central nervous system abnormalities in half of the individuals. PMID: 24882706
    2. CCDC41 is required for the docking of ciliary vesicles PMID: 23530209
  • 相關疾病：
    Nephronophthisis 18 (NPHP18)
  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes specifically to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane. Localizes to centrioles at all stages of the cell cycle, including mitosis.
  • 蛋白家族：
    CEP83 family
  • 數據庫鏈接：

    HGNC: 17966

    OMIM: 615847

    KEGG: hsa:51134

    STRING: 9606.ENSP00000344655

    UniGene: Hs.279209



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