在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CEP192 Antibody

CEP192 Antibody

  • 中文名稱：
    CEP192兔多克隆抗體
  • 貨號：
    CSB-PA851560LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA851560LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA851560LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) CEP192 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CEP192
  • 別名：
    CEP192 antibody; KIAA1569 antibody; PP8407Centrosomal protein of 192 kDa antibody; Cep192 antibody; Cep192/SPD-2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Centrosomal protein of 192 kDa protein (447-711AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，CEP192 Antibody (CSB-PA851560LA01HU)，的標記方式是Non-conjugated。對于CEP192 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA851560LB01HU CEP192 Antibody, HRP conjugated ELISA
    FITC CSB-PA851560LC01HU CEP192 Antibody, FITC conjugated
    Biotin CSB-PA851560LD01HU CEP192 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Required for mitotic centrosome maturation and bipolar spindle assembly. Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication. Centrosome-specific activating scaffold for AURKA and PLK1.
  • 基因功能參考文獻：
    1. Study shows that the interaction between Cep295 and Cep192 seems to be crucial for the integrity of centriole structure and also for daughter-to-mother centriole conversion. PMID: 27562453
    2. Here we demonstrate that CEP192 also recruits the type one protein phosphatase (PP1) via a highly conserved KHVTF docking motif. PMID: 28188792
    3. Interphase cells depleted of Cep192 display significantly higher levels of centrosome-associated Pericentrin while overexpression of Cep192 reduces the levels of centrosomal Pericentrin. PMID: 24971877
    4. Plk1 promotes centrosome-based bipolar spindle formation by forming two functionally nonredundant complexes with Cep192. PMID: 26012549
    5. Study identifies a Cep192-organized signaling cascade that underlies both centrosome maturation and bipolar spindle assembly. PMID: 25042804
    6. Plk4 is intricately regulated in time and space through ordered interactions with two distinct scaffolds, Cep192 and Cep152, and a failure in this process may lead to human cancer. PMID: 24997597
    7. Loss of the Cep192- or Cep152-dependent interaction with Plk4 resulted in impaired centriole duplication that led to delayed cell proliferation. PMID: 24277814
    8. cooperation between Cep192 and Cep152 is crucial for centriole recruitment of Plk4 and centriole duplication during the cell cycle. PMID: 23641073
    9. By modulating Cep192 levels, PHD1 thereby affects the processes of centriole duplication and centrosome maturation and contributes to the regulation of cell-cycle progression. PMID: 23932902
    10. CEP192 promotes robust mitotic spindle assembly by regulating K63-polyubiquitin-mediated signaling through CYLD. PMID: 22895009
    11. Cep192-mediated mechanism maximizes AurA activity at centrosomes and appears essential for the function of these organelles as primary microtubule -organizing centers. PMID: 21097701
    12. Cep192 stimulates the formation of the scaffolding upon which gamma-tubulin ring complexes and other proteins involved in microtubule nucleation and spindle assembly become functional during mitosis. PMID: 17980596
    13. major regulator of pericentriolar material recruitment, centrosome maturation, and centriole duplication in mammalian cells PMID: 18207742

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Pericentriolar location in mitotic centrosomes.
  • 數據庫鏈接：

    HGNC: 25515

    OMIM: 616426

    KEGG: hsa:55125

    STRING: 9606.ENSP00000427550

    UniGene: Hs.100914



主站蜘蛛池模板： 少妇激情一区二区三区视频小说| 性色av一区二区三区人妻| 亚洲精品国产av成拍色拍婷婷| 在线成人www免费观看视频| 美女啪啪网站又黄又免费| 新国产精品视频福利免费| 56pao国产成视频永久| 日产精品久久久一区二区| 国产乱妇无乱码大黄aa片| 免费无码av片在线观看国产| 亚洲日韩中文字幕在线不卡最新| 亚洲一区二区三区小说| 人人妻人人澡人人爽欧美一区 | 国模无码大尺度一区二区三区| 国内少妇偷人精品免费| 美女mm131午夜福利在线| 亚洲国产婷婷综合在线精品| 亚洲日韩中文字幕一区| 国产高清午夜人成在线观看| 99热成人精品国产免费| 国产乱色国产精品播放视频 | 男女猛烈无遮挡免费视频app| 午夜精品乱人伦小说区| 亚洲熟妇久久精品| 欧美国产激情一区二区在线| 精品国产在天天在线观看| 久久午夜无码鲁丝片午夜精品| 国内老熟妇对白hdxxxx| 久久www色情成人免费| 午夜成人性刺激免费视频| 欧美另类videossexo高潮| 欧美成人免费全部| 日产精品1区2区3区| 午夜福利伦伦电影理论片在线观看| 99re热视频这里只精品| av在线 高清不卡区| 农村乱人伦一区二区| 欧美亚洲日韩国产人成在线播放| 永久免费观看黄网视频| 国产高清色高清在线观看| 国产黄a三级三级三级av在线看|