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  4. CEP170 Antibody

CEP170 Antibody

  • 中文名稱：
    CEP170兔多克隆抗體
  • 貨號：
    CSB-PA001570
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of AD293 cells using CEP170 Polyclonal Antibody
    • Western Blot analysis of MCF7 PC-3 Hela cells using CEP170 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    CEP170
  • 別名：
    CEP170 antibody; FAM68A antibody; KAB antibody; KIAA0470Centrosomal protein of 170 kDa antibody; Cep170 antibody; KARP-1-binding protein antibody; KARP1-binding protein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human CEP170.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays a role in microtubule organization. Required for centriole subdistal appendage assembly.
  • 基因功能參考文獻：
    1. Data suggest that CDK5RAP2 and CEP170 both interact with microtubule nucleation-promoting region of AKAP350A; CEP68 interacts with distal C-terminal region of AKAP350A; AKAP350A spans the bridge between centrioles. (CDK5RAP2 = CDK5 regulatory subunit associated protein 2; CEP170 = centrosomal protein 170kDa; AKAP350A = A kinase (PRKA) anchor protein (yotiao) 9; CEP68 = centrosomal protein 68kDa) PMID: 29054927
    2. Data indicate that Cep170 association with the C-terminus of Kif2b enhances localization of Kif2b to the spindle. PMID: 23087211
    3. Cep170 interacts with Polo-like kinase 1 in mature centrioles. PMID: 15616186
  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle.
  • 蛋白家族：
    CEP170 family
  • 數據庫鏈接：

    HGNC: 28920

    OMIM: 613023

    KEGG: hsa:9859

    STRING: 9606.ENSP00000355500

    UniGene: Hs.533635



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