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  4. CELSR3 Antibody, HRP conjugated

CELSR3 Antibody, HRP conjugated

  • 中文名稱：
    CELSR3兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA852817LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) CELSR3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Anchor protein antibody; Cadherin EGF LAG seven-pass G-type receptor 3 antibody; Cadherin family member 11 antibody; CDHF11 antibody; CELR3_HUMAN antibody; Celsr3 antibody; EGF like domain multiple 1 antibody; EGF-like protein 1 antibody; EGFL1 antibody; Epidermal growth factor-like protein 1 antibody; Flamingo antibody; Flamingo homolog 1 antibody; FMI1 antibody; hFmi1 antibody; MEGF2 antibody; Multiple EGF-like domains protein 2 antibody; Multiple epidermal growth factor-like domains protein 2 antibody; RESDA1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Cadherin EGF LAG seven-pass G-type receptor 3 protein (514-718AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Receptor that may have an important role in cell/cell signaling during nervous system formation.
  • 基因功能參考文獻：
    1. Study identifies four likely Tourette disorder risk genes with multiple de novo damaging variants in unrelated probands: WWC1 (WW and C2 domain containing 1), CELSR3 (Cadherin EGF LAG seven-pass G-type receptor 3), NIPBL (Nipped-B-like), and FN1 (fibronectin 1). PMID: 28472652
    2. marked reduction in the prominence of TUJ1 bundles in number, thickness, and length. Our results showed that deregulation of the planar cell polarity genes CELSR3 and FZD3 might disrupt the enteric innervation pattern PMID: 27619161
    3. A moderate positive correlation between CELSR3 and patient age was also evident. PMID: 26838213
    4. seven-transmembrane domain receptors Celsr3 and Fzd3, in particular, control the development of most longitudinal tracts in the central nervous system. [Review] PMID: 25813877
    5. CELSR3 promoter hypermethylation is associated with oral squamous cell carcinoma. PMID: 25374236
    6. CELSR3 was found to be selectively up-regulated in tumor stellate cells. PMID: 20416094
    7. CELSR3 is one of the core PCP signaling molecules. PMID: 16273260

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  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 2 family, LN-TM7 subfamily
  • 數據庫鏈接：

    HGNC: 3230

    OMIM: 604264

    KEGG: hsa:1951

    STRING: 9606.ENSP00000164024

    UniGene: Hs.631926



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