在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CDKN2A Antibody

  • 中文名稱:
    CDKN2A兔多克隆抗體
  • 貨號:
    CSB-PA003615
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of HeLa cells using p14 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    CDKN2A antibody; CDKN2 antibody; MLM antibody; Tumor suppressor ARF antibody; Alternative reading frame antibody; ARF antibody; Cyclin-dependent kinase inhibitor 2A antibody; p14ARF antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human p14.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IHC, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. Binds to BCL6 and down-regulates BCL6-induced transcriptional repression. Binds to E2F1 and MYC and blocks their transcriptional activator activity but has no effect on MYC transcriptional repression. Binds to TOP1/TOPOI and stimulates its activity. This complex binds to rRNA gene promoters and may play a role in rRNA transcription and/or maturation. Interacts with NPM1/B23 and promotes its polyubiquitination and degradation, thus inhibiting rRNA processing. Interacts with COMMD1 and promotes its 'Lys63'-linked polyubiquitination. Interacts with UBE2I/UBC9 and enhances sumoylation of a number of its binding partners including MDM2 and E2F1. Binds to HUWE1 and represses its ubiquitin ligase activity. May play a role in controlling cell proliferation and apoptosis during mammary gland development. Isoform smARF may be involved in regulation of autophagy and caspase-independent cell death; the short-lived mitochondrial isoform is stabilized by C1QBP.
  • 亞細胞定位:
    Nucleus, nucleolus. Nucleus, nucleoplasm.; [Isoform smARF]: Mitochondrion.
  • 數據庫鏈接:

    HGNC: 1787

    OMIM: 600160

    UniGene: Hs.512599



主站蜘蛛池模板: 国产日韩在线视看第一页| 亚洲中文无码永久免| 真实国产乱子伦对白在线播放| av人摸人人人澡人人超碰妓女| 男女裸交免费无遮挡全过程| 妖精色av无码国产在线看| 超清精品丝袜国产自在线拍| 韩国三级中文字幕hd| 久久婷婷五月综合色一区二区| 午夜免费无码福利视频麻豆| 肥白大屁股bbwbbwhd| 中文字幕一区二区三区四区五区| 中文在线最新版天堂| 成人国产片视频在线观看| 99国产欧美久久久精品| 精品国产亚洲一区二区三区| 黄页网站视频| 久久久久久久精品成人执小说一白| 亚洲欧美人成网站aaa| 色偷偷色噜噜狠狠网站年轻人| 九九久久精品无码专区| 97国产精品人妻无码久久久| 在线观看潮喷失禁大喷水无码 | 亚洲а∨天堂男人色无码| 亚洲另类无码一区二区三区| aa片在线观看视频在线播放| 中文字日产乱码免费1~3软件| 狠狠色噜噜狠狠狠777米奇888| 精品乱子伦一区二区三区| 色偷偷av男人的天堂| 亚洲国产成人无码av在线影院 | 免费一区二区无码东京热 | 国产成人无码av一区二区| 久久无码人妻精品一区二区三区| 久久综合九色综合97婷婷| 国产成人亚洲综合无码品善网| 精品国模一区二区三区| 无码人妻啪啪一区二区| 最新69国产成人精品视频| 国产亚洲精品影视在线| 国产一区二区|