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  4. CDK2AP2 Antibody

CDK2AP2 Antibody

  • 中文名稱：
    CDK2AP2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA006440
  • 規(guī)格：
    ￥1090
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    CDK2AP2
  • 別名：
    CDK2AP2 antibody; DOC1RCyclin-dependent kinase 2-associated protein 2 antibody; CDK2-associated protein 2 antibody; DOC-1-related protein antibody; DOC-1R antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human DOC-1R.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes. Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A.
  • 基因功能參考文獻(xiàn)：
    1. Our findings suggest that alteration of p16, p14, p27, p21, and p53 status may contribute to carcinogenesis and the clinical behavior of HPV-negative adenocarcinoma of the uterine cervix PMID: 25675191
    2. antitumor effects of DOC-1R may be mediated by negatively regulating G1 phase progression and G1/S transition through inhibiting CDK2 expression and activation PMID: 23781148
  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    CDK2AP family
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 30833

    KEGG: hsa:10263

    STRING: 9606.ENSP00000301488

    UniGene: Hs.523835



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