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CDH16 Antibody

  • 中文名稱:
    CDH16兔多克隆抗體
  • 貨號:
    CSB-PA005041ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA005041ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CDH16 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    CAD16_HUMAN antibody; Cadherin 16 antibody; Cadherin 16 KSP cadherin antibody; Cadherin kidney antibody; Cadherin-16 antibody; CDH 16 antibody; CDH16 antibody; Kidney cadherin antibody; Kidney specific cadherin antibody; Kidney-specific cadherin antibody; Ksp cadherin antibody; Ksp-cadherin antibody; PRO1340 antibody; UNQ695 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Cadherin-16 protein (19-230AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
  • 基因功能參考文獻:
    1. Our study expands the clinical and allelic spectrum of known Retinal dystrophies genes, and reveals AGBL5, CDH16, and DNAJC17 as novel disease candidates. PMID: 26355662
    2. In thyroid carcinomas, as determined by quantitative RT-PCR, CDH16 expression decreases in papillary, follicular, and anaplastic thyroid carcinomas, and the decrease is more pronounced than that of CDH1. PMID: 22028439
    3. These results indicated that LIF induced multi-lineage differentiation of adult stem-like cells in kidney via cadherin 16. PMID: 15670782
    4. Ksp-cadherin expression downregulated inrenal cell carcinoma; this cell adhesion molecule may have role in tumour suppression PMID: 15886705
    5. Ksp-cad is a useful tumor type associated marker for distinguishing chromophobe renal cell carcinoma and renal oncocytoma from the wide range of nonintercalated cell-related adult renal epithelial neoplasms. PMID: 17895753
    6. The interaction of Ksp-cadherin with alpha B-crystallin is important for the connection of Ksp-cadherin to the cytoskeleton and thus for maintaining tissue integrity in the kidney. PMID: 18343407

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  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 組織特異性:
    Kidney specific.
  • 數據庫鏈接:

    HGNC: 1755

    OMIM: 603118

    KEGG: hsa:1014

    STRING: 9606.ENSP00000299752

    UniGene: Hs.513660



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