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CD300LB Antibody

  • 中文名稱：
    CD300LB兔多克隆抗體
  • 貨號(hào)：
    CSB-PA004919LA01HU
  • 規(guī)格：
    ￥440
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) CD300LB Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CD300LB
  • 別名：
    CD300LB antibody; CD300B antibody; CLM7 antibody; CMRF35A2 antibody; IREM3 antibody; LMIR5 antibody; TREM5 antibody; UNQ2530/PRO6029CMRF35-like molecule 7 antibody; CLM-7 antibody; CD300 antigen-like family member B antibody; CMRF35-A2 antibody; Immune receptor expressed on myeloid cells 3 antibody; IREM-3 antibody; Leukocyte mono-Ig-like receptor 5 antibody; Triggering receptor expressed on myeloid cells 5 antibody; TREM-5 antibody; CD antigen CD300b antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human CMRF35-like molecule 7 protein (18-151AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，CD300LB Antibody (CSB-PA004919LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于CD300LB Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA004919LB01HU CD300LB Antibody, HRP conjugated ELISA
    FITC CSB-PA004919LC01HU CD300LB Antibody, FITC conjugated
    Biotin CSB-PA004919LD01HU CD300LB Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2.
  • 基因功能參考文獻(xiàn)：
    1. this paper identified CD300b as an lipopolysaccharide-recognizing receptor that regulated TLR4 signaling PMID: 27261276
    2. CD300LB expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
    3. CD300 molecules are all expressed by DC; CD300b, d, e and f are restricted to different subpopulations of the myeloid DC lineage. They have been shown to regulate DC function both in vitro and in vivo. PMID: 23072861
    4. CD300b defines a nonclassical Ig receptor able to trigger signals by coupling distinct mediators and thus initiating different signaling pathways PMID: 16920917
    5. although both mouse and human LMIR5 play activatory roles in innate immunity cells, the functions of LMIR5 were differentially regulated in mouse versus human cells. PMID: 17928527

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  • 亞細(xì)胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    CD300 family
  • 組織特異性：
    Expressed exclusively in myeloid lineages.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30811

    OMIM: 610705

    KEGG: hsa:124599

    STRING: 9606.ENSP00000376397

    UniGene: Hs.313343



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