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CCT3 Antibody

  • 中文名稱:
    CCT3兔多克隆抗體
  • 貨號:
    CSB-PA004857ESR1HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: T-complex protein 1 subunit gamma antibody at 12μg/ml + Mouse brain tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 61, 57 kDa
      Observed band size: 61 kDa
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA004857ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA004857ESR1HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CCT3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    CCT3
  • 別名:
    CCT 3 antibody; CCT gamma antibody; CCT-gamma antibody; CCT3 antibody; CCTG antibody; Chaperonin containing TCP1 subunit 3 (gamma) antibody; Chaperonin containing TCP1 subunit 3 antibody; hTRiC5 antibody; PIG48 antibody; T complex protein 1 gamma subunit antibody; T complex protein 1 subunit gamma antibody; T-complex protein 1 subunit gamma antibody; TCP 1 gamma antibody; TCP-1-gamma antibody; TCP1 (t complex 1) ring complex polypeptide 5 antibody; TCPG_HUMAN antibody; TRIC5 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human T-complex protein 1 subunit gamma protein (1-300AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.
  • 基因功能參考文獻:
    1. Suggest that CCT3 is indispensible for hepatocellular carcinoma cell proliferation, and provides a potential drug target for treatment of HCC. PMID: 26739059
    2. Overexpression of CCT3 in the nuclei of cancerous cells is associated with hepatocellular carcinoma progression. CCT3 may be a target that affects the activation of STAT3 in HCC. PMID: 26229401
    3. Expression of S100A9 and CCTgamma was significantly elevated in liver tissue of patients with cholangiocarcinoma compared with controls. PMID: 23868055
    4. Among ten hepatocellular carcinoma cases with amplicon 1q21-q22, significant gene expression level of JTB, SHC1, CCT3 and COPA in the tumors than the paired adjacent non-malignant liver tissues. PMID: 12586295
  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    TCP-1 chaperonin family
  • 數據庫鏈接:

    HGNC: 1616

    OMIM: 600114

    KEGG: hsa:7203

    STRING: 9606.ENSP00000295688

    UniGene: Hs.491494



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