在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CCNL1 Antibody

  • 中文名稱:
    CCNL1兔多克隆抗體
  • 貨號:
    CSB-PA986857
  • 規(guī)格:
    ¥2024
  • 圖片:
    • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Cyclin-L1 antibody.
    • Western blot analysis of extracts from HepG2 cells, using Cyclin-L1 antibody.
    • Western blot analysis of extracts from HeLa cells (Lane 2), A549 cells (Lane 3) and HepG2 cells (Lane 4), using Cyclin-L1 antiobdy. The lane on the left is treated with systhesized peptide.
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) CCNL1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from Human Cyclin-L1.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs). Inhibited by the CDK-specific inhibitor CDKN1A/p21. May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC).
  • 基因功能參考文獻:
    1. Results suggest that LEKR1-CCNL1 and IGSF21-KLHDC7A gene polymorphisms influence the development of diabetic retinopathy (DR). PMID: 27607899
    2. CCNL1 is the target gene of miR-199b-5p. PMID: 26043836
    3. Data indicate that if the newborn carried a risk allele rs900400 near LEKR/CCNL1, the impact of stress on birth size was stronger. PMID: 22685556
    4. birth weight lowering effect of the C-allele of rs900400 located near LEKR1 and CCNL1 was replicated in the Danish population. Furthermore the C-allele was associated with increased insulin response following oral glucose stimulation PMID: 22073261
    5. Data show low birth weight in Asian Indians is not due to variation near CCNL1/ADCY5, but variant ADCY5 is associated with elevated glucose/decreased insulin response which suggests a common genetic cause of low birth weight and risk of type 2 diabetes. PMID: 21712988
    6. These data demonstrate that there is a fine balance between CCNL1 and TIMP1, which may contribute to breast cancer development. PMID: 21586274
    7. Our results suggest that a genetic variant of ccnl1 leads to symmetric growth restriction from early pregnancy onward PMID: 21307140
    8. Cyclin L1 amplification is associated with uterine cervical carcinoma. PMID: 20721974
    9. variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight PMID: 20372150
    10. role in pre-mRNA splicing PMID: 11980906
    11. Our results indicate that CCNL1 plays a critical role in the loco-regional progression of HNSCC and may serve as an indicator for occult advanced tumour stages. PMID: 15700036
    12. study suggests that cyclin l1 may have a role in RNA processing complex anc ould participate in tumor progression of head and neck squamous cell carcinoma PMID: 16598186
    13. Data show that a green fluorescent protein (GFP) fusion protein of cyclin L1, in contrast to cyclin L2, was not mobile within the nucleus of living COS7 cells. PMID: 17494991
    14. CDK11(p110) interacts physically and functionally with cyclin Lalpha and -beta isoforms and SR proteins to regulate splicing. PMID: 18216018
    15. Cyclin L has been shown to associate with the PITSLRE kinase and is involved in pre-mRNA processing. PMID: 11980906

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus speckle. Nucleus, nucleoplasm.
  • 蛋白家族:
    Cyclin family, Cyclin L subfamily
  • 組織特異性:
    Widely expressed. Overexpression in primary tumors of head and neck squamous cell carcinomas (HNSCC).
  • 數(shù)據(jù)庫鏈接:

    HGNC: 20569

    OMIM: 613384

    KEGG: hsa:57018

    STRING: 9606.ENSP00000295926

    UniGene: Hs.4859



主站蜘蛛池模板: 亚洲精品尤物av在线观看不卡| 超薄丝袜足j好爽在线| 国产午夜成人久久无码一区二区| 无码不卡av东京热毛片| 又粗又黄又硬又爽的免费视频| 免费人成视频在线观看不卡| 被c到高潮疯狂喷水国产| 97夜夜澡人人双人人人喊| 欧美黑人乱大交| 97香蕉碰碰人妻国产欧美| 欧美两根一起进3p做受视频| 国产综合有码无码视频在线| 成人网站免费高清视频在线观看 | 亚洲国产综合在线观看不卡| 在线天堂资源www中文| 藏春阁福利视频| 亚洲码国产精品高潮在线| 久久精品女人的天堂av| 看国产黄大片在线观看| 少妇无码av无码一区| 天堂网在线观看| 亚洲精品色在线网站| 无码国产精品一区二区免费vr| 捆绑白丝粉色jk震动捧喷白浆| 天堂中文在线8最新版地址 | 欧美人与动性xxxxx杂| 99久无码中文字幕一本久道| 国产aⅴ爽av久久久久久| 日本熟妇厨房bbw| 中文无码乱人伦中文视频在线| 国产精品美女www爽爽爽视频| 久久中文精品无码中文字幕| 四虎影视永久免费观看在线| 18禁在线永久免费观看| 长腿校花无力呻吟娇喘| 欧美处交wwwvideos另类| 新版天堂资源中文8在线| 日本十八禁视频无遮挡| 亚洲免费综合色在线视频| 无码帝国www无码专区色综合| 中文字幕精品亚洲无线码二区|