在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CBR3 Antibody

CBR3 Antibody

  • 中文名稱：
    CBR3兔多克隆抗體
  • 貨號：
    CSB-PA001212
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of MCF7 cells using Carbonyl Reductase 3 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    CBR3
  • 別名：
    Carbonyl reductase (NADPH) 3 antibody; Carbonyl reductase (NADPH) 3 EC 1.1.1.184 antibody; Carbonyl reductase [NADPH] 3 antibody; Carbonyl reductase 3 antibody; CBR 3 antibody; CBR3 antibody; CBR3_HUMAN antibody; EC 1.1.1.184 antibody; Epididymis secretory protein Li 25 antibody; hCBR3 antibody; HEL S 25 antibody; NADPH dependent carbonyl reductase 3 antibody; NADPH-dependent carbonyl reductase 3 antibody; SDR21C2 antibody; Short chain dehydrogenase/reductase family 21C member 2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Carbonyl Reductase 3.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro).
  • 基因功能參考文獻：
    1. CBR3 730G>A is significantly associated with recurrence- free survival in patients who received intravesical chemotherapy with pirarubicin after complete transurethral resection. PMID: 30125887
    2. No significant correlation between cardiotoxicity and SNPs within the CBR pathway. Further investigation into CBR SNPs in a larger adult sample is needed. PMID: 26563179
    3. association of SNPs in ABCB1 and CBR3 with chronic cardiotoxicity in a cohort of breast cancer patients treated with anthracyclines. PMID: 26799497
    4. Variants of CBR3 and GSTP1 enzymes may be associated with changes in short-term functional cardiac parameters. PMID: 23182048
    5. genetic polymorphism in the CBR3 gene conferred risk of type 2 diabetes and insulin resistance in Chinese. The association was probably mediated through modulation of adipogenesis. PMID: 22527884
    6. CBR3 polymorphisms contribute to increased cardiomyopathy risk associated with anthracycline treatment of childhood cancer. PMID: 22124095
    7. CBR3 is a novel target gene of inflammatory stimuli; elucidation of its detailed role in inflammation deserves further investigation. PMID: 22425771
    8. Computational searches identify a conserved antioxidant response element(ARE) in the distal carbonyl reductase 3 (CBR3) promoter region. PMID: 22001310
    9. The CBR3 distal promoter contains an activating cis-regulatory element that is responsive to Trichostatin A (TSA) treatment according to promoter reporter assays in HEK 293 cells. PMID: 20494980
    10. CBR3 is regulated via NRF2-dependent signaling pathways, a finding and plays an important role in the cellular response to oxidative stress. PMID: 20806931
    11. analysis of the structural basis for substrate specificity in human monomeric carbonyl reductases CBR3 PMID: 19841672
    12. The common carbonyl reductase 3 (CBR3)valine244methionine polymorphism encodes for CBR3 isoforms with distinctive enzymatic properties, as revealed in DNA variation panels from 10 ethnic groups. PMID: 15537833
    13. There was a trend toward an association between the CBR3 V244M polymorphism and the risk of CHf PMID: 18457324
    14. Polymorphisms in CBR3 may explain interindividual and interethnic variability of doxorubicin pharmacokinetics and pharmacodynamics. PMID: 18551042
    15. CBR3 polymorphisms have no significant influence on the pharmacokinetics of doxorubicin in Asian breast cancer patients. PMID: 19016765
    16. identified the promoter of human CBR3. Liver samples from black donors showed higher relative CBR3 mRNA levels than samples from whites PMID: 19590938
    17. carbonyl reductase has an important function in modifying the metastatic behavior of malignant tumors. PMID: 10728668
    18. Decreased Carbonyl Reductase expression in epithelial ovarian cancer is associated with RLN metastasis and poor survival PMID: 11592776

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    Short-chain dehydrogenases/reductases (SDR) family
  • 組織特異性：
    Detected in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 1549

    OMIM: 603608

    KEGG: hsa:874

    STRING: 9606.ENSP00000290354

    UniGene: Hs.154510



主站蜘蛛池模板： 久久中文字幕人妻熟av女| 狠狠五月深爱婷婷网| 中文乱码字幕视频观看网站免费 | av蓝导航精品导航| 日日摸日日碰夜夜爽无码| 漂亮人妻被强中文字幕久久| 婷婷色香五月综合激激情| 日韩欧美人妻一区二区三区 | 亚洲日本va午夜中文字幕久久| 18成禁人视频免费| 亚洲 日韩 国产欧美 另类| 国产后入又长又硬| 四虎国产成人永久精品免费| 中文乱码人妻系列一区| 国产偷久久久精品专区| 国产在线观看www污污污| 亚洲中文字幕无码久久2017| 四虎亚洲中文字幕无码永久| 女人被狂爆到高潮免费视频| 中文人妻av大区中文不卡| 浓毛欧美老妇乱子伦视频 | 亚洲人成人影院在线观看| 日日碰狠狠躁久久躁婷婷| 成人午夜高潮a∨猛片| 欧美亚洲国产精品久久| 99久久久国产精品消防器材| 粉嫩小泬无遮挡久久久久久 | 午夜亚洲国产理论片中文飘花| 伊人久久精品无码麻豆一区| 中文字幕亚洲欧美日韩在线不卡| 亚洲精品久久久久久下一站| 成人无码精品一区二区三区| 久久不见久久见免费影院视频| 无码国内精品久久人妻| 国产午夜成人免费看片| 无码专区—va亚洲v专区vr| 亚洲国产制服丝袜先锋| 国产精品久久久久久久久久直播| 无码人妻精品一区二区三区99不卡| 日韩精品人妻系列一区二区三区| 国产精品午夜剧场免费观看|