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  4. CARD18 Antibody

CARD18 Antibody

  • 中文名稱：
    CARD18兔多克隆抗體
  • 貨號：
    CSB-PA004521LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA004521LA01HU diluted at 1:100 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) CARD18 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    CARD18 antibody; ICEBERG antibody; UNQ5804/PRO19611Caspase recruitment domain-containing protein 18 antibody; Caspase-1 inhibitor Iceberg antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Caspase recruitment domain-containing protein 18 protein (1-90AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，CARD18 Antibody (CSB-PA004521LA01HU)，的標記方式是Non-conjugated。對于CARD18 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA004521LB01HU CARD18 Antibody, HRP conjugated ELISA
    FITC CSB-PA004521LC01HU CARD18 Antibody, FITC conjugated
    Biotin CSB-PA004521LD01HU CARD18 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B.
  • 基因功能參考文獻：
    1. In lesional epidermis of patients with lichen planus, CARD18 expression was either greatly diminished or entirely absent whereas in non-lesional areas expression was comparable to normal skin. PMID: 28506683
    2. CARD18 expression differs in healthy and psoriatic skin; moreover, CARD18 demonstrated altered response under inflammatory conditions in healthy and psoriatic skin PMID: 27023378
    3. CARD18 may be both a promising marker for prognosis and a target protein for treatment of gastric cancer. PMID: 23948415
  • 組織特異性：
    Primarily expressed in the heart and placenta.
  • 數據庫鏈接：

    HGNC: 28861

    OMIM: 605354

    KEGG: hsa:59082

    STRING: 9606.ENSP00000436691

    UniGene: Hs.56279



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