在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CARD10 Antibody

  • 中文名稱:
    CARD10兔多克隆抗體
  • 貨號:
    CSB-PA001213
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of 293 cells using CARD 10 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Bcl10 binding protein and activator of NFKB antibody; BIMP1 antibody; CAR10_HUMAN antibody; CARD 10 antibody; CARD containing MAGUK 3 protein antibody; CARD-containing MAGUK 3 antibody; CARD-containing MAGUK protein 3 antibody; CARD10 antibody; Carma 3 antibody; CARMA3 antibody; Caspase Recruitment Domain family member 10 antibody; Caspase recruitment domain-containing protein 10 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human CARD 10.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IHC, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:10000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Activates NF-kappa-B via BCL10 and IKK.
  • 基因功能參考文獻:
    1. The results suggest that the involvement of CARMA3 in DNA damage-induced NF-kappaB is through the recruitment of TRAF6. PMID: 28717989
    2. Card10 polymorphisms may not be linked with psoriasis vulgaris in the southern Han Chinese population. PMID: 28301668
    3. Data indicate no association between caspase recruitment domain family, member 10 protein (CARD10) polymorphism rs6000782 and type 1 autoimmune hepatitis (AIH) in a Japanese population. PMID: 26652023
    4. Findings indicate that CARMA3 may suppress the activation of the P38 MAPK signaling pathway to regulate invasion, migration and apoptosis of lung cancer cells by activating NF-small ka, CyrillicB (P65) in the nucleus. PMID: 26526492
    5. miR-24 inhibited cell proliferation, invasion and epithelial to mesenchymal transition in bladder cancer cells by downregulation of CARMA3 PMID: 26252200
    6. The study identified the DEP domain-containing protein DEPDC7 as cellular binding partner of CARMA2 and CARMA3 proteins. PMID: 25541973
    7. A novel mechanism of CARMA3 in lung cancer stemness and metastasis through the negative regulation of NME2 was identified. PMID: 25906011
    8. CARMA3 regulates the ovarian cancer cell proliferation, cell cycle progression, and chemoresistance. PMID: 24833094
    9. CARMA3 is overexpressed in pancreatic cancer and regulates malignant cell growth, invasion, and NF-kappaB signaling, which was dependent on its association with Bcl10. PMID: 24633921
    10. CARMA3 is overexpressed in bladder cancer and regulates malignant cell growth and NF-kappaB signaling. PMID: 24443255
    11. Genetic variation within PARP1 and CARD10 was associated with rate of hippocampal neurodegeneration in APOE e3/e3 patients. PMID: 23608917
    12. CARD10 may be involved in hepatic carcinogenesis associated with hepatitis C in Egyptian patients. PMID: 24018495
    13. overexpression of CARMA3 in human glioma and its correlation with tumor grade. PMID: 23893382
    14. Data show that CARMA3 may serve as a novel and prognostic marker for renal cell carcinoma (RCC) and play a role during the development and progression of the disease. PMID: 23771851
    15. CARMA3 facilitates proliferation and inhibits apoptosis through nuclear factor-kappaB signaling. PMID: 23708960
    16. this study found that CARMA3 is overexpressed in colon cancers and contributes to malignant cell growth by facilitating cell cycle progression through NF-kappaB mediated upregulation of cyclin D1. PMID: 22884800
    17. The overexpression of CARMA3 was significantly correlated with TNM stage (P = 0.022) and tumor status (P = 0.013). PMID: 22615840
    18. Polymorphisms of ATOH7, TGFBR3 and CARD10 influence the size of optic disc area. PMID: 21307088
    19. Data show that CARMA3 and Bcl10 contributed to several characteristics of EGFR-associated malignancy, including proliferation, survival, migration, and invasion. PMID: 21406399
    20. CARMA1 and CARMA3 bind to Ikappa kinase gamma-NFkappaB in B and T lymphocytes PMID: 15184390
    21. Protein kinase C-CARMA3 signaling axis plays an essential role in lysophosphatidic acid-induced ovarian cancer cell in vitro invasion. PMID: 17724468
    22. results further define the molecular mechanisms that control activation of NF-kappaB and reveal a function for A20 in the regulation of CARMA and BCL10 activity in lymphoid and non-lymphoid cells PMID: 18349075
    23. Data demonstrate that lysophosphatidic acid stimulates thymic stromal lymphopoietin and CCL20 expression in bronchial epithelial cells via CARMA3-mediated NF-kappaB activation. PMID: 18757306

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 組織特異性:
    Detected in adult heart, kidney and liver; lower levels in intestine, placenta, muscle and lung. Also found in fetal lung, liver and kidney.
  • 數據庫鏈接:

    HGNC: 16422

    OMIM: 607209

    KEGG: hsa:29775

    STRING: 9606.ENSP00000251973

    UniGene: Hs.57973



主站蜘蛛池模板: 成人免费精品网站在线观看影片| 国产成人8x人在线视频软件| 天天躁日日躁狠狠躁人妻| 五月天精品视频在线观看| 国产特级毛片aaaaaa高潮流水| 国产又色又爽无遮挡免费| 日本国产成人国产在线播放| 男女边吃奶边做边爱视频| 夫妇交换性三中文字幕| 内射少妇36p亚洲区| 色欲人妻aaaaaa无码| 羞国产在线拍揄自揄视频| 久久国产欧美日韩精品| 国产熟妇高潮呻吟喷水| 最新69成人精品视频免费 | 久久99热狠狠色精品一区| 热99re久久精品| 国产69精品久久久久乱码韩国| 手机真实国产乱子伦对白视频| 国产丝袜美女一区二区三区| 骚片av蜜桃精品一区| 综合久久—本道中文字幕| 又黄又爽又色视频| 动漫精品啪啪一区二区三区| 亚洲gv天堂gv无码男同| 亚洲.日韩.欧美另类| 婷婷色婷婷开心五月四房播播| 欧洲多毛裸体xxxxx| 99热久久这里只精品国产www| 国产微拍精品一区二区| 人人妻人人澡人人爽人人精品av | av无码小缝喷白浆在线观看| 97国产超碰一区二区三区| 手机看片久久国产免费| 亚洲欧美一区二区成人片| 久久婷婷丁香七月色综合| 无码一区二区三区av在线播放 | 欧洲精品一卡2卡三卡4卡影视| 国产精品天干天干| 亚洲久悠悠色悠在线播放| 国产xxxx色视频在线观看|