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  4. CAMK2N2 Antibody

CAMK2N2 Antibody

  • 中文名稱：
    CAMK2N2兔多克隆抗體
  • 貨號：
    CSB-PA004470NA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of MCF-7 cells with CSB-PA004470NA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) CAMK2N2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CAMK2N2
  • 別名：
    CAMK2N2Calcium/calmodulin-dependent protein kinase II inhibitor 2 antibody; CaM-KII inhibitory protein antibody; CaM-KIIN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Peptide sequence from Human Calcium/calmodulin-dependent protein kinase II inhibitor 2 protein (10-28AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，CAMK2N2 Antibody (CSB-PA004470NA01HU)，的標記方式是Non-conjugated。對于CAMK2N2 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應用
    HRP CSB-PA004470NB01HU CAMK2N2 Antibody, HRP conjugated ELISA
    FITC CSB-PA004470NC01HU CAMK2N2 Antibody, FITC conjugated
    Biotin CSB-PA004470ND01HU CAMK2N2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2. May play an important role in the regulation of cell growth when overexpressed in colon adenocarcinoma LoVo cells. Traps Ca(2+)/calmodulin on CAMK2.
  • 基因功能參考文獻：
    1. Mutant FUS-DeltaNLS increased calcium/calmodulin-dependent protein kinase II inhibitor 2 (CAMK2N2) at both mRNA and protein levels. PMID: 23545117
    2. Murine double minute 2 (MDM2) protein levels were decreased in AD cells relative to control lymphoblasts, suggesting an impairment of FOXO3a degradation. PMID: 23153928
    3. We show that CaMKII N beta expression is differentially regulated by novelty and contextual fear conditioning, providing further insight into molecular basis of fear LTM. PMID: 20487031
    4. hCaMKIINbeta may play an important role in the regulation of tumor cell growth PMID: 19586909
    5. Functional study of the rat homolog PMID: 9724800

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  • 亞細胞定位：
    Nucleus. Cytoplasm, cytosol.
  • 蛋白家族：
    CAMK2N family
  • 組織特異性：
    Expressed in cell lines including hemopoietic cell lines and some tumor cell lines. Highly Expressed in stimulated dendritic cell (DC) and weakly expressed in unstimulated mature and immature DC. Highly expressed in kidney, liver, in cell lines HeLaS3, ly
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24197

    OMIM: 608721

    KEGG: hsa:94032

    STRING: 9606.ENSP00000296238

    UniGene: Hs.585003



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