在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CALU Antibody

  • 中文名稱:
    CALU兔多克隆抗體
  • 貨號:
    CSB-PA004460GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    CALU
  • 別名:
    CALU antibody; CALU_HUMAN antibody; Calumenin 1 antibody; Calumenin 2 antibody; Calumenin antibody; Crocalbin antibody; crocalbin-like protein antibody; FLJ90608 antibody; IEF SSP 9302 antibody; multiple EF-hand protein antibody; OTTHUMP00000212712 antibody; OTTHUMP00000212713 antibody; OTTHUMP00000212714 antibody; OTTHUMP00000212715 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human CALU
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity.
  • 基因功能參考文獻:
    1. Replacing Leu with Gly (L150G) in Calu1 enables the protein to adopt a structural fold even in the Ca(2+) free form. The fourth (of seven) EF-hand of HsCalu1 nucleates the structural fold of the protein depending on the switch residue (Gly or Leu). PMID: 29319298
    2. The Calumenin modulates Sarco/Endoplasmic reticulumCa2+ATPase (SERCA) pump activity without drastically affecting ER-Ca(2+) concentration. PMID: 28189267
    3. Calu-15, a novel isoform of Calu with phosphorylation-dependent nuclear localization, has a critical role in promoting filopodia formation and cell migration by upregulating the GDF-15 transcription. PMID: 24136234
    4. Results provide direct evidence for the involvement of CALU and LGALS3BP as potential negative regulators in the virus-triggered induction of the typeI interferons. PMID: 26124285
    5. Results show that OSBPL5 and CALU were expressed at higher levels in the lung tissues of metastasis-positive cases than that in the metastasis-negative cases suggesting they can promote invasiveness of lung cancer cells. PMID: 25963840
    6. CALU polymorphism A29809G affects calumenin availability involving vascular calcification PMID: 25823396
    7. Calumenin is characterized as a charged protein exhibiting close similarity with intrinsically disordered proteins and is hypothesized to regulate F508del-CFTR folding by electrostatic effects. PMID: 25120007
    8. Calumenin is a new CFTR chaperone. PMID: 22768251
    9. Study found the secretion of calu-1/2-EGFP required microtubule integrity, and that calu-1/2-EGFP-containing vesicles were transported by the motor proteins Kif5b and cytoplasmic dynein. PMID: 22514732
    10. Quantitative PCR assays for VKORC1, CYP4F2, GGCX and CALU identified two copies in all populations. PMID: 22188360
    11. associated with arterial calcification and short-term prognosis of the outcome of patients with non-ST-elevation acute coronary syndrome PMID: 20673165
    12. Data show that calumenin in the presence of calcium binds specifically to thrombospondin-1, but closely-related reticulocalbin does not form a similar complex. PMID: 18688696

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum membrane. Golgi apparatus. Secreted. Melanosome. Sarcoplasmic reticulum lumen.
  • 蛋白家族:
    CREC family
  • 組織特異性:
    Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver.
  • 數據庫鏈接:

    HGNC: 1458

    OMIM: 603420

    KEGG: hsa:813

    STRING: 9606.ENSP00000420381

    UniGene: Hs.743262



主站蜘蛛池模板: 香蕉啪视频在线观看视频久| 亚洲成av人片高潮喷水| 亚洲一卡一卡二新区迎热烈讨论| 97人人超碰国产精品最新| 国产精品久久久久久亚洲色| 人妻丰满熟妇岳av无码区hd | 亚洲欧美另类成人综合图片| 人妻无码少妇一区二区| 男人狂躁进女人下面免费视频| 曰批免费视频播放免费| 日本最新免费二区三区| 亚洲精品国产第一区第二| 亚洲精品宾馆在线精品酒店| www.一区二区三区在线 | 欧洲| 久久精品国产精品国产精品污| 最近中文字幕mv在线资源| 国产亚洲高清国产拍精品| 亚洲国产成人超a在线播放| 久久精品人人做人人爽97| 疯狂的欧美乱大交| 亚洲性无码av在线欣赏网| 成人啪啪高潮不断观看| 国产免费爽爽视频在线观看| 久久精品水蜜桃av综合天堂| 成年性生交大片免费看| 狠狠色丁香婷婷久久综合| 色欲av亚洲情无码av蜜桃| 国产亚洲人成网站在线观看| 久久久国产乱子伦精品作者| 国产午夜伦鲁鲁| 久久精品99av高久久精品| 色偷偷偷久久伊人大杳蕉| 国产免费又黄又爽又色毛| 一本一道波多野结衣av一区| 精品av国产一二三四区| 熟女人妻高清一区二区三区| 国产亚洲精品久久久久的角色| 中文字幕乱码人妻一区二区三区| 久久亚洲精品ab无码播放| 国产未成女一区二区| 欧美顶级少妇做爰hd|