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  4. CA5B Antibody

CA5B Antibody

  • 中文名稱：
    CA5B兔多克隆抗體
  • 貨號：
    CSB-PA006799
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of 3T3 cells using CA VB Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    CA5B
  • 別名：
    CA VB antibody; CA-VB antibody; CA5B antibody; CAH5B_HUMAN antibody; Carbonate dehydratase VB antibody; Carbonic anhydrase 5B antibody; Carbonic anhydrase 5B; mitochondrial antibody; Carbonic anhydrase VB antibody; Carbonic anhydrase VB; mitochondrial antibody; mitochondrial antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human CA VB.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Reversible hydration of carbon dioxide.
  • 基因功能參考文獻：
    1. In 10 of 96 patients, mutations in CA5A were identified on both alleles but none in CA5B. Exhibiting decreased enzyme activity or thermal stability, all CAVA mutations were proven to cause disease, whereas the three variants showed no relevant effect PMID: 26913920
    2. activators enhanced kcat, with no effect on KM, favoring the RDS in the catalytic cycle; the activation pattern of the two mitochondrial isoforms is very different from each other and as compared to those of the cytosolic isoforms hCA I and II. PMID: 17174092
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    Alpha-carbonic anhydrase family
  • 組織特異性：
    Strongest expression in heart, pancreas, kidney, placenta, lung, and skeletal muscle. Not expressed in liver.
  • 數據庫鏈接：

    HGNC: 1378

    OMIM: 300230

    KEGG: hsa:11238

    STRING: 9606.ENSP00000314099

    UniGene: Hs.653287



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