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CA3 Antibody

  • 中文名稱:
    CA3兔多克隆抗體
  • 貨號:
    CSB-PA298167
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA298167(CA3 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane: Human fetal kidney tissue, Primary antibody: CSB-PA298167(CA3 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    CA3
  • 別名:
    CA III antibody; CA-III antibody; Ca3 antibody; CAH3_HUMAN antibody; CAIII antibody; Car3 antibody; Carbonate dehydratase III antibody; Carbonic anhydrase 3 antibody; Carbonic anhydrase III antibody; Carbonic anhydrase III muscle specific antibody; EC 4.2.1.1 antibody; Epididymis secretory sperm binding protein Li 167mP antibody; HEL S 167mP antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human CA3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    WB 1:200-1:1000
    IHC 1:10-1:50
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Reversible hydration of carbon dioxide.
  • 基因功能參考文獻:
    1. CAIII and Hsp70 expressions were higher in LPRD patients that in non-LPRD patients, suggesting the possibility as one of biomomarker in LPRD diagnosis. PMID: 26847302
    2. this study detected the formation and colocalization of 6-nitrotryptophan-containing proteins and CAIII in the skin of atopic dermatitis patients, not only in the lesional part but also in the nonlesional part, through histochemical analyses PMID: 24838180
    3. Report that anti-CAIII antibodies may be useful for diagnosing microscopic polyangiitis. PMID: 23981757
    4. The carbonic anhydrase CA3 isoform displayed an increased abundance during muscle aging, which was independently verified by immunoblotting of differently aged human skeletal muscle samples. PMID: 22797148
    5. The generation of CA III and IV autoantibodies, antioxidant enzymes, and cytokines might influence each other. PMID: 23049597
    6. Crystallization and preliminary X-ray analysis of human carbonic anhydrase III PMID: 11976500
    7. Data show that inserting histidine residues into the active site cavity of carbonic anhydrase II or III results in rates of proton transfer to the zinc-bound hydroxide that are antagonistic or suppressive with respect to the corresponding single mutants. PMID: 12171926
    8. Proton transfer within the active-site cavity of carbonic anhydrase III PMID: 12484342
    9. myoglobin/carbonic anhydrase III ratio in the blood proved to be a more specific indicator for myocardial damage than myoglobin alone after myocardial infarction. PMID: 12745799
    10. CAIII expression is upregulated in kidney cortex samples from the end-stage kidney of a patient with Dent's disease owing to the G506E mutation of CLCN5 PMID: 18322545
    11. CAIII promotes transformation and invasion capability in hepatoma cells through FAK signaling pathway. PMID: 18444244
    12. The level of CAIII is specifically insufficient in the skeletal muscle of myasthenia gravis patients. PMID: 19301202

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  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Alpha-carbonic anhydrase family
  • 組織特異性:
    Muscle specific.
  • 數據庫鏈接:

    HGNC: 1374

    OMIM: 114750

    KEGG: hsa:761

    STRING: 9606.ENSP00000285381

    UniGene: Hs.82129



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