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C9orf89 Antibody

  • 中文名稱:
    C9orf89兔多克隆抗體
  • 貨號:
    CSB-PA070012
  • 規(guī)格:
    ¥1090
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    CARD19
  • 別名:
    Bcl10 interacting protein with CARD protein antibody; Bcl10-interacting CARD protein antibody; BINCA_HUMAN antibody; BinCARD antibody; C9orf89 antibody; Chromosome 9 open reading frame 89 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human BinCARD.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.
  • 基因功能參考文獻:
    1. the crystal structure of BinCARD reveals that all three cysteines were oxidized PMID: 23633586
    2. BinCard inhibits BCL10-mediated activation of NF-kappa B. PMID: 15637807
  • 亞細胞定位:
    [Isoform 1]: Nucleus. Note=Coexpression with BCL10 induced translocation from nucleus to cytosol.; [Isoform 2]: Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
  • 組織特異性:
    Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 28148

    OMIM: 617726

    KEGG: hsa:84270

    UniGene: Hs.434213



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