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C6 Antibody

  • 中文名稱:
    C6兔多克隆抗體
  • 貨號:
    CSB-PA001093
  • 規(guī)格:
    ¥1090
  • 圖片:
    • Western Blot analysis of HuvEc cells using C6 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    AW111623 antibody; C6 antibody; CO6_HUMAN antibody; Complement component 6 antibody; Complement component C6 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Rat
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human C6.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
  • 基因功能參考文獻:
    1. Our study provided novel evidence that genetic variations in complement genes C6 and MASP1were associated with preeclampsia risk, and that the risk varied by preeclampsia subtypes PMID: 27405496
    2. recipient C6 rs9200 polymorphism is associated with HCC recurrence after OLT, and improves the predictive value of clinical models. PMID: 27173880
    3. Structure of complement C6 suggests a mechanism for initiation and unidirectional, sequential assembly of membrane attack complex (MAC). PMID: 22267737
    4. finding of very high serious morbidity in patients with complete C6 deficiency due to meningococcal infections PMID: 22288589
    5. Genetic polymorphisms in C6 gene do not influence the risk of aspirin hypersensitivity in Korean asthmatic patients. PMID: 21704099
    6. produced by trophoblast cells PMID: 19665237
    7. The most common defect, which leads to an increased susceptibility to Neisseria meningitidis infections in the Western Cape, is 879delG. PMID: 17257682

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  • 相關疾病:
    Complement component 6 deficiency (C6D)
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Complement C6/C7/C8/C9 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 1339

    OMIM: 217050

    KEGG: hsa:729

    STRING: 9606.ENSP00000263413

    UniGene: Hs.481992



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