在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. C1QC Antibody, HRP conjugated

C1QC Antibody, HRP conjugated

  • 中文名稱：
    C1QC兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA003641LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) C1QC Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    AI385742 antibody; C1Q C antibody; C1qc antibody; C1QC_HUMAN antibody; C1QG antibody; Complement C1q subcomponent subunit C antibody; Complement component 1; q subcomponent; C chain antibody; complement component 1; q subcomponent; gamma polypeptide antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Complement C1q subcomponent subunit C protein (27-157AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
  • 基因功能參考文獻(xiàn)：
    1. Neuromyelitis optica patients had higher levels of C3a and anti-C1q antibodies than healthy controls. PMID: 25109258
    2. C1q deficiency due to a Gly164Ser mutation may have a role in Rothmund-Thomson syndrome and glomerulonephritis [case report] PMID: 24157463
    3. C1q and C1q receptor interaction may be responsible for the C1q-mediated migration of mesenchymal stromal cells. PMID: 22264191
    4. Three single nucleotide polymorphisms (STAT6 rs703817, C1qG rs17433222, and MBP rs3794845) were found to be significantly associated with childhood leukemia risk in Koreans. PMID: 20438785
    5. These results suggest a novel pathway in which C1q and MBL influence removal and metabolism of atherogenic forms of LDL in the early stages of atherosclerosis. PMID: 20833838
    6. prevents monocyte-derived dendritic cell differentiation PMID: 19710097
    7. The C-terminal globular region of the C1Q C chain may have evolved as a functionally specialized domain or module with distinct binding properties which together with the A and B chains confers versatility and flexibility to the whole C1q molecule. PMID: 12847249
    8. Complementary interacting sites on the C1q globular domain have been precisely defined. Characterization of point mutants suggests a complementary role for Arg156 of C1Q C chain in the C1q-IgG interaction. PMID: 15034050
    9. C1q polymorphisms are associated with SLE, serum C1q and CH50 levels in a stable founder population of patients with SLE. PMID: 18504288
    10. The peripheral globular region of the C1q molecule displays a lectin-like activity, which contributes to DNA binding through interaction with its deoxy-d-ribose moiety and may participate in apoptotic cell recognition. PMID: 18703056
    11. Complement C1q chemoattracts human dendritic cells and enhances migration of mature dendritic cells to CCL19 via activation of AKT and MAPK pathways.( PMID: 18838169
    12. Complement protein C1q and anti-hexon antibodies together can mediate efficient adenovirus infection in coxsackie and adenovirus receptor-negative cell types. PMID: 19115936
    13. C1QC (rs9434) correlates with later age of onset in TTR Val30Met familial amyloidotic polyneuropathy. C1QC (rs15940) does not. PMID: 19493541
    14. C1q deficiency is such a strong risk factor for systemic lupus erythematosus. PMID: 19790049

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Complement component C1q deficiency (C1QD)
  • 亞細(xì)胞定位：
    Secreted.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 1245

    OMIM: 120575

    KEGG: hsa:714

    STRING: 9606.ENSP00000363768

    UniGene: Hs.467753



主站蜘蛛池模板： 人人爽人人爱| 久久大香线蕉国产精品免费| 久久99亚洲精品久久频| 中文字幕人妻色偷偷久久 | 97人妻无码专区| 欧洲免费一区二区三区视频| 波多野结衣不打码视频| 人妻夜夜爽天天爽三区麻豆av网站| 亚洲精品～无码抽插| 国产精品白丝久久av网站| 国产成熟女人性满足视频| 国精一二二产品无人区免费应用| 天天躁日日躁很很很躁| 国产香港明星裸体xxxx视频| 日日日日做夜夜夜夜做无码| 中国猛少妇色xxxxx| 性欧美丰满熟妇xxxx性仙踪林| 日本老熟妇毛茸茸| 无码中文字幕人妻在线一区| 无码三级在线看中文字幕完整版| 国产高颜值大学生情侣酒店| 亚洲乱亚洲乱妇24p| 美日欧激情av大片免费观看| 无码加勒比一区二区三区四区 | 成人无码一区二区三区网站| 日韩av无码免费播放| 欧美丰满老熟妇xxxxx性| av无码电影一区二区三区| 欲色欲色天天天www| 久久久精品2019免费观看| 亚洲最大成人网 色香蕉| 亚洲精品成a人在线观看| 国产精品亚洲专区无码web| 国产精品成人一区二区不卡| 国产裸体xxxx视频| 99久久无码一区人妻| 青青草无码伊人久久| 亚洲区激情区无码区日韩区 | 国产日产亚洲系列最新| 亚洲精品国精品久久99热| 又爆又大又粗又硬又黄的a片|