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  4. BTN3A2 Antibody, HRP conjugated

BTN3A2 Antibody, HRP conjugated

  • 中文名稱：
    BTN3A2兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA002874LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) BTN3A2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    BTN3A2
  • 別名：
    BT3.2 antibody; BT3.3 antibody; BT3A2_HUMAN antibody; BTF4 antibody; BTN3A 2 antibody; BTN3A2 antibody; Butyrophilin protein antibody; Butyrophilin subfamily 3 member A2 antibody; Butyrophilin; subfamily 3; member A2 antibody; CD277 antibody; FLJ40011 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Butyrophilin subfamily 3 member A2 protein (30-248AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.
  • 基因功能參考文獻：
    1. CpG-specific DNA methylation of ADAMTSL2 and BTN3A2 at rheumatoid arthritis diagnosis can serve as a marker of treatment response. PMID: 28447857
    2. BTN3A2 genetic variants have role in gastric carcinogenesis. PMID: 28246015
    3. BTN3A2 rs9104 was strongly associated with genotype 1 hepatitis C infection. PMID: 25928882
    4. Three SNPs in BTN3A2 were associated with schizophrenia, rs12214031, rs9393709 and rs12199613. There was no interaction between these SNPs and HSV-1, CMV or toxoplasma exposure. PMID: 22966150
    5. Results suggest that BT3.2 butyrophilin expression by epithelial cells may modulates the intratumoral infiltration of immune cells. PMID: 22685580
    6. our results identify PRSS16 and BTN3A2, two genes thought to play important roles in regulating the immune response, as potentially novel susceptibility genes for Type I Deabetes. PMID: 19295542

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  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Immunoglobulin superfamily, BTN/MOG family
  • 組織特異性：
    Detected in T-cells and natural killer cells.
  • 數據庫鏈接：

    HGNC: 1139

    OMIM: 613594

    KEGG: hsa:11118

    STRING: 9606.ENSP00000348751

    UniGene: Hs.376046



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