在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. BTG1 Antibody

BTG1 Antibody

  • 中文名稱：
    BTG1兔多克隆抗體
  • 貨號：
    CSB-PA192473
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA192473(BTG1 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA192473(BTG1 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    BTG1Protein BTG1 antibody; B-cell translocation gene 1 protein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human BTG1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:15-1:50
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Anti-proliferative protein.
  • 基因功能參考文獻：
    1. This study demonstrated for the first time that lower expression of BTG1 correlated with poor survival in PDAC patients, which suggests that BTG1 expression may serve as an available prognostic biomarker in the future PMID: 29076521
    2. BTG1 expression is lowered in colorectal cancer cells. Forced BTG1 expression reverses aggressive phenotypes in colorectal cancers. PMID: 27447746
    3. BTG1 down-regulation in colorectal cancer occurs through epigenetic repression, which is involved in the development and progression of colorectal cancer. PMID: 29374692
    4. BTG1 gene deletion is associated with acute lymphoblastic leukemia. PMID: 28033648
    5. our results identify BTG1 as a tumor suppressor in leukemia that, when deleted, strongly enhances the risk of relapse in IKZF1-deleted B-cell precursor acute lymphoblastic leukemia, and augments the glucocorticoid resistance phenotype mediated by the loss of IKZF1 function. PMID: 27979924
    6. BTG1 interacts with ATF4 and positively modulates its activity by recruiting the protein arginine methyl transferase PRMT1 to methylate ATF4 on arginine residue 239. PMID: 26657730
    7. our data suggest that BTG1 overexpression combined with radiation therapy increases the therapeutic efficacy of breast cancer treatment via regulation of the cell cycle and apoptosis-related signaling pathways. PMID: 26503430
    8. Suggest that down-regulated BTG1 expression might promote gastric carcinogenesis partially due to its promoter methylation. BTG1 overexpression might reverse the aggressive phenotypes. PMID: 26050197
    9. Reduced BTG1 expression is associated with increased nasopharyngeal cancer severity, suggesting it is a negative regulator of the cancer and can serve as a prognostic indicator. Reduced BTG1 expression is possibly associated with tumour metastasis. PMID: 24985971
    10. Our results indicate that altered BTG1 expression might affect hepatocarcinogenesis and may represent a novel biomarker for HCC carcinogenesis and progression. PMID: 25405901
    11. Data indicate that microRNA-19a regulates prostate cancer cells by directly targeting B cell translocation gene-1 protein BTG1. PMID: 25936765
    12. Altered expression of BTG1 is a potential biomarker for carcinogenesis and progression of gastric cancer, particularly for proximal nondiffuse and diffuse GC. PMID: 25487193
    13. Results show that reduced BTG1 expression is associated with increased disease severity, suggesting it as negative regulator of thyroid cancer. PMID: 25017022
    14. Down-regulation of BTG1 by miR-454-3p renders tumor cells sensitive to radiation. PMID: 25115181
    15. BTG1 protein levels were significantly reduced in hepatocellular cancer and were associated with lymph node metastasis, clinical stage, cell differentiation, and prognosis. PMID: 25173640
    16. Bcell translocation 1 gene inhibits cellular metastasisassociated behavior in breast cancer. PMID: 24714932
    17. Reduced BTG1 expression is associated with increased disease severity, suggesting it is a negative regulator of esophageal cancer PMID: 24969561
    18. BTG1 deletions might play a role in leukemogenesis of B-cell precursor acute lymphoblastic leukemia as well as of BCR-ABL1-positive mixed-phenotype acute leukemia and chronic myeloid leukemia in B-lineage blast crisis (B-lineage). PMID: 24998463
    19. BTG1 may play important roles as a negative regulator to breast cancer cell. PMID: 24272202
    20. BTG1 expression decreased in nonsmall cell lung cancer and correlated significantly with lymph node metastasis; clinical stage; histological grade; poor overall survival PMID: 24264312
    21. Altered BTG1 expression might play a role in the pathogenesis. PMID: 24084718
    22. These results indicate that BTG1 may be used as a novel therapeutic target for human breast cancer treatment. PMID: 23982470
    23. BTG1 deletions are not associated with down syndrome acute lymphoblastic leukemia PMID: 22868968
    24. BTG1 loss is a novel finding in acute lymphoblastic leukemia in children with down syndrome PMID: 22072402
    25. BTG1 regulates glucocorticoid receptor autoinduction in acute lymphoblastic leukemia. PMID: 20354172
    26. Antiproliferative proteins of the BTG/Tob family are degraded by the ubiquitin-proteasome system. the C-terminal regions are necessary and sufficient to control the stabilities of BTG1, BTG2, Tob, and Tob2 proteins. PMID: 12135500
    27. FoxO3a controls expression of BTG1 and subsequent regulation of protein arginine methyl transferase activity. PMID: 14734530
    28. BTG1 may play an important role in the process of angiogenesis PMID: 15033446
    29. BTG1 is a novel important coactivator involved in the regulation of myoblast differentiation. PMID: 15674337
    30. five genes (TNFSF10/TRAIL, IL1RN, IFI27, GZMB, and CCR5) were upregulated and three genes (CLK1, TNFAIP3 and BTG1) were downregulated in at least three out of four subpopulations during acute GVHD. PMID: 18814951
    31. These findings support the hypothesis that BTG1 polymorphisms may influence genetic predisposition for MS, especially in relapse-onset MS patients. PMID: 19515430

    顯示更多

    收起更多

  • 相關疾?。?/div>
    A chromosomal aberration involving BTG1 may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with MYC.
  • 蛋白家族：
    BTG family
  • 數據庫鏈接：

    HGNC: 1130

    OMIM: 109580

    KEGG: hsa:694

    STRING: 9606.ENSP00000256015

    UniGene: Hs.255935



主站蜘蛛池模板： 国内精品久久久久精免费| 丰满五十六十老熟女hd| 中文字幕无码不卡一区二区三区| 国产乱码日产精品bd| 色综合久久中文字幕有码| 久久国产乱子伦免费精品| 中文有码无码人妻在线| 精品亚洲一区二区三区在线观看| 动漫精品专区一区二区三区不卡| 国产亚洲中文字幕在线制服| 男男又爽又黄又无遮挡网站| 国产亚洲精品久久久久蜜臀| 无码人妻久久一区二区三区不卡 | 天堂在/线中文在线资源8| 裸体丰满白嫩大尺度尤物| 一个人看的www片免费高清视频| 十八禁视频网站在线观看| 一本久道久久综合狠狠躁av| 被窝影院午夜无码国产| 377p欧洲日本亚洲大胆| 久久99亚洲精品久久99果| 婷婷久久综合九色综合绿巨人| 日本黄漫动漫在线观看视频| 亚洲精品国产一区黑色丝袜| 亚洲综合无码精品一区二区三区| 日韩去日本高清在线| 精品亚洲国产成人av制服| 99精品国产成人一区二区| 久久综合丝袜日本网| 玩弄丰满熟妇xxxxx性60| 久久久国产精品人人片| 亚洲国产一区二区三区| 久久综合给合久久国产免费| 18禁成人黄网站免费观看久久| 欧美老熟妇videos极品另类| 日本一区二区三区免费更新不卡 | 国产成年无码久久久久下载 | 丰满人妻一区二区三区视频53| 中文字幕日韩精品亚洲一区 | 无码一区二区三区老色鬼| 欧洲美女黑人粗性暴交|