在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

BTD Antibody

  • 中文名稱:
    BTD兔多克隆抗體
  • 貨號:
    CSB-PA002854LA01HU
  • 規格:
    ¥440
  • 圖片:
    • IHC image of CSB-PA002854LA01HU diluted at 1:400 and staining in paraffin-embedded human melanoma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) BTD Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    BTD
  • 別名:
    Biotinase antibody; Biotinidase antibody; Btd antibody; BTD_HUMAN antibody; EC 3.5.1.12 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Biotinidase protein (322-397AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,BTD Antibody (CSB-PA002854LA01HU),的標記方式是Non-conjugated。對于BTD Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA002854LB01HU BTD Antibody, HRP conjugated ELISA
    FITC CSB-PA002854LC01HU BTD Antibody, FITC conjugated
    Biotin CSB-PA002854LD01HU BTD Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation.
  • 基因功能參考文獻:
    1. BTD mutation is associated with biotinidase deficiency. PMID: 29995633
    2. Biotinidase deficiency is reviewed. PMID: 26577040
    3. Four rare missense variants were identified (ACTBL2 rs73757391 (5q11.2), BTD rs200337373 (3p25.1), KRT13 rs150321809 (17q21.2) and MC2R rs104894658 (18p11.21)), but only MC2R rs104894668 had a large effect size (OR = 9.66). PMID: 27378695
    4. The history and genetic basis of biotinidase deficiency has been presented. (Review) PMID: 26456103
    5. 48 novel alterations in the biotinidase gene have been identified; correlating the individual's serum enzymatic activity with genotype, were able to determine the effect of the novel alteration on enzyme activity and, thereby, determine its likelihood of being pathogenic in 44 of these individuals PMID: 26810761
    6. The common biotinidase gene mutations (p.R157H, p.D444H, c.98-104del7ins3, p.T532M) cumulatively accounted for 72.3% of all the mutant alleles in the Turkish population. PMID: 25754625
    7. Summary of the demographic features of patients identified as biotinidase deficient from August of 2012 through August of 2013 and mutation analysis results for 20 cases in the southeast region of Turkey. PMID: 25423671
    8. Three novel pathogenic variants in BTD gene were identified in a cohort of Brazilian patients with biotinidase deficiency and control suggesting an allelic heteregeneity of the condition. PMID: 25174816
    9. Report incidence of profound biotinase deficiency in Swedish newborns and adoptive immigrant children. PMID: 20224900
    10. High frequencies of biotinidase mutations may explain the high incidence of biotinidase deficiency in Hungary. PMID: 20549359
    11. Mutation analysis revealed three novel mutations, c.del631C and c.1557T>G within exon 4 and c.324-325insTA in exon 3 in Biotinidase deficiency patients and families. PMID: 23481307
    12. Four Somali patients have the P497S mutation, with one of the four being homozygous for the mutation PMID: 19757147
    13. Six different mutations in the biotinidase gene are identified in biotinidase in four Chinese patients; determination of biotinidase activities are performed for selective screening of biotinidase deficiency PMID: 19728141
    14. loss of overall biotinidase expression is a novel marker for thyroid cancer aggressiveness. PMID: 22911723
    15. Plasma BTD activity increases in hepatic glycogen storage disease patients. PMID: 20532819
    16. 140 known mutations in the biotinidase gene (BTD) that cause biotinidase deficiency, are reported. PMID: 20556795
    17. Mutations in biotinidase is associated with biotinidase deficiency. PMID: 20539236
    18. 12 patients with multiple carboxylase deficiency, six mutations were found in the BT gene and 4 in the HLCS gene, including 5 novel mutations. PMID: 19806568
    19. review of mutations causing biotinidase deficiency PMID: 11668630
    20. report of 17 novel mutations that cause profound biotinidase deficiency. Six of the mutations are due to deletions, whereas the remaining 11 mutations are missense mutations located throughout the gene PMID: 12359137
    21. analysis of mutations in biotinidase deficiency PMID: 15776412
    22. 21 different mutations were identified in 49 patients, including four novel mutations. Ten mutations proved to be unique to the Hungarian population. PMID: 17185019
    23. Posttranslational modification of histones by biotinylation can be catalyzed by biotinidase; role of this function is ambiguous. PMID: 18479898
    24. This case indicates that biotinidase deficiency should be included in the differential diagnosis of subacute myelopathy and emphasizes the importance of a prompt diagnosis to prevent irreversible neurological damage. PMID: 18645204

    顯示更多

    收起更多

  • 相關疾病:
    Biotinidase deficiency (BTD deficiency)
  • 亞細胞定位:
    Secreted, extracellular space.
  • 蛋白家族:
    Carbon-nitrogen hydrolase superfamily, BTD/VNN family
  • 數據庫鏈接:

    HGNC: 1122

    OMIM: 253260

    KEGG: hsa:686

    STRING: 9606.ENSP00000306477

    UniGene: Hs.444197



主站蜘蛛池模板: 亚洲欭美日韩颜射在线| 男人猛戳女人30分钟视频大全| 爆乳高潮喷水无码正在播放| 中文字幕亚洲一区二区三区| 日本熟妇大屁股人妻| 国产v综合v亚洲欧美久久| 欧美亚洲色aⅴ大片| 国产精品无码dvd在线观看| 亚洲精品永久在线观看| 国产成人麻豆精品午夜福利在线| 天天摸夜夜添狠狠添高潮出水 | 成人免费无码大片a毛片| 女人张开腿让男桶喷水高潮| 亚洲第一最快av网站| 久久综合九色综合欧洲98| 国产午夜亚洲精品国产成人小说| 精品夜夜澡人妻无码av| 无码人妻精品一区二区三区免费| 粉嫩大学生无套内射无码卡视频| 乱人伦人妻中文字幕无码 | 国内露脸中年夫妇交换| 女人被狂爆到高潮免费视频 | 久久久久99精品成人片| 成人片黄网站a毛片免费| 无码熟熟妇丰满人妻啪啪| 亚洲国产成人久久精品99| 久久婷婷五月综合97色| 亚洲综合在线另类色区奇米| 午夜福制92视频| 欧美黑人巨大videos精品| 亚洲成av人片在线观看无码不卡| 玩弄少妇的肉体k8经典| 十八禁无码免费网站| 亚洲欧美中文日韩v在线观看| 一本一道vs无码中文字幕| 亚洲国产区男人本色vr| 青青草原综合久久大伊人| 日本黄页网站免费观看| 国产亚洲精品久久久ai换脸| 亚洲精品久久久久玩吗| 中文www新版资源在线|