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BRI3BP Antibody

  • 中文名稱:
    BRI3BP兔多克隆抗體
  • 貨號(hào):
    CSB-PA007304
  • 規(guī)格:
    ¥1090
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    BRI3BP
  • 別名:
    BRI3BP; KG19; BRI3-binding protein; I3-binding protein; Cervical cancer 1 proto-oncogene-binding protein KG19; HCCRBP-1
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from the N-terminal region of Human KG19.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    WB, IHC, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Involved in tumorigenesis and may function by stabilizing p53/TP53.
  • 基因功能參考文獻(xiàn):
    1. HCCRBP-3 induces tumorigenesis through direct interaction with HCCR-1 in human cancers. PMID: 22851403
    2. highly expressed in brain, kidney, and liver; mapped to human chromosome 12q24.2-qter PMID: 11860200
    3. Taken together, BRI3BP, widely expressed in animal cell types, seems to possess a pro-apoptotic property and can potentiate drug-induced apoptosis. PMID: 17765869
  • 亞細(xì)胞定位:
    Mitochondrion outer membrane; Multi-pass membrane protein.
  • 組織特異性:
    Most abundantly expressed in brain, liver and kidney. Overexpressed in leukemia and lymphoma cell lines, as well as in various carcinomas.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 14251

    OMIM: 615627

    KEGG: hsa:140707

    STRING: 9606.ENSP00000340761

    UniGene: Hs.596464



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