在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. BMP5 Antibody

BMP5 Antibody

  • 中文名稱：
    BMP5兔多克隆抗體
  • 貨號：
    CSB-PA001026
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HuvEC cells using BMP-5 Polyclonal Antibody
    • Western Blot analysis of VEC 293 A549 cells using BMP-5 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    BMP 5 antibody; BMP-5 antibody; Bmp5 antibody; BMP5_HUMAN antibody; Bone morphogenetic protein 5 antibody; MGC34244 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human BMP-5.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cartilage and bone formation or neurogenesis. Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes. Can also signal through non-canonical pathway such as MAPK p38 signaling cascade to promote chondrogenic differentiation.
  • 基因功能參考文獻：
    1. Suggest a significant role of miR-32/BMP5 axis in colorectal cancer tumorigenesis. PMID: 30119170
    2. findings suggested that BMP5 might be a potential prognostic biomarker or therapeutic target for patients with NSCLC PMID: 25994008
    3. Our results showed that ASPN rs13301537 T to C change and variant C genotype may contribute to knee OA risk in a Chinese Han population. PMID: 25030405
    4. Data indicate significant association between the bone morphogenetic protein 5 (BMP5) microsatellite and knee osteoarthritis (OA) in women, but not in men. PMID: 23186552
    5. BMP5, is elevated in the stenotic colon segment of Hirschsprung disease patients, and BMP5 signaling may play a pivotal role in disease development. PMID: 24551273
    6. BMP5 and BMP7, involved in cardiomyocyte differentiation defect PMID: 24384427
    7. CASP3 rs4862396, BMP5 rs3734444 and IRS2 rs7986346 may affect the survival in patients after androgen-deprivation therapy for prostate cancer PMID: 22844442
    8. BMP-5 is expressed in the tubuli of adult kidneys. Its decreased expression in nephrosclerosis along with its regenerative capabilities in HK-2 cells may point to a protective role in hypertensive nephrosclerosis. PMID: 21319131
    9. Taken together, BMP4 and BMP5 simultaneously inhibit the growth and promote migration and invasion of the same pancreatic cells and thus exhibit a biphasic role with both detrimental and beneficial functions in pancreatic cancer progression PMID: 21704030
    10. Variability in gene expression of BMP5 may be an important contributor to osteoarthritis genetic susceptibility PMID: 20021689
    11. The expression signals of BMP-5 mRNA in malignant schwannoma were relatively lower than in benign lesions PMID: 11642720
    12. BMP-5 increases the levels of osteopontin, BMP-2, alkaline phosphatase and core binding factor alpha 1 mRNAs in human periodontal (HPL) ligament cells. PMID: 15516325
    13. BMP5 is expressed in normal synovial tissue and was decreased in osteoarthritis and rheumatoid arthritis. PMID: 16542506
    14. The differential allelic expression (DAE) of BMP5 in human mesenchymal tissues obtained from 16 donors undergoing joint replacement for treatment of osteoarthritis, was examined. PMID: 17220169

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    TGF-beta family
  • 組織特異性：
    Expressed in the lung and liver.
  • 數據庫鏈接：

    HGNC: 1072

    OMIM: 112265

    KEGG: hsa:653

    STRING: 9606.ENSP00000359866

    UniGene: Hs.296648



主站蜘蛛池模板： 无码播放一区二区三区| 色欲av久久综合人妻无码| 国产成人无码免费视频97| 久久国国产免费999| 女女女女女裸体处开bbb| 非洲人与性动交ccoo| 亚洲欧洲无码一区二区三区| 最新的国产成人精品2022| 免费无码成人av片在线在线播放 | 宝宝好涨水快流出来免费视频| 丁香激情综合久久伊人久久| 东北女人毛多水多牲交视频| 老熟妇乱子交视频一区| 四虎国产精品永久在线无码| 免费无码又爽又刺激聊天app| 精品无码一区二区三区在线| 亚洲欧洲日韩极速播放| 国内精品久久久久影院免费| 亚洲精品久久国产高清小说| 日韩a片无码毛片免费看| 欧美自拍嘿咻内射在线观看 | 欧美乱大交aaaa片if| 亚洲精品色情app在线下载观看| 久久综合香蕉国产蜜臀av| 我的公把我弄高潮了视频| 美女极度色诱视频国产免费| 青青久久成人免费影院| 久久精品99国产精品日本| 精品国产美女福到在线不卡| 在线天堂新版最新版在线8 | 欧美成人看片一区二三区图文| 8x国产精品视频| 无码丰满熟妇| 午夜在线a亚洲v天堂网2018| 日韩欧美精品有码在线| 少妇被粗大的猛烈进出视频| 中文字幕丰满乱孑伦无码专区| 成人精品一区二区三区电影免费| 又粗又硬又黄又爽的视频永久| 天天爽夜夜爽人人爽曰| 中文无码成人免费视频在线观看 |