在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

BMF Antibody

  • 中文名稱:
    BMF兔多克隆抗體
  • 貨號:
    CSB-PA850383ESR1HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA850383ESR1HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) BMF Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    BMF
  • 別名:
    Bcl 2 modifying factor antibody; Bcl-2-modifying factor antibody; Bcl2 modifying factor antibody; Bmf antibody; BMF_HUMAN antibody; FLJ00065 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Bcl-2-modifying factor protein (1-184AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    May play a role in apoptosis. Isoform 1 seems to be the main initiator.
  • 基因功能參考文獻:
    1. The findings are consistent with rs539846 influencing chronic lymphocytic leukemia (CLL) susceptibility through differential RELA binding, with direct modulation of BMF expression impacting on anti-apoptotic BCL2, a hallmark of oncogenic dependency in CLL. PMID: 27524613
    2. Reciprocal regulation of BMF and BIRC5 is linked to Eomes overexpression in colorectal cancer. PMID: 27539959
    3. Early generated B1 B cells with restricted BCRs become chronic lymphocytic leukemia with continued c-Myc and low Bmf expression PMID: 27899442
    4. these findings suggest that p53-R273H can specifically drive AKT signaling and suppress BMF expression, resulting in enhanced cell survivability and anoikis resistance. PMID: 26181206
    5. Overexpression of ApoL2 did not induce cell death on its own. ApoL2 did not sensitize or protect cells from overexpression of the BH3-only proteins Bmf or Noxa. PMID: 24901046
    6. Diva binds peptides derived from the BH3 domain of several other proapoptotic Bcl-2 proteins, including mouse Harakiri, Bid, Bak and Bmf. PMID: 23192964
    7. BMF is induced in human IEC by the loss of cell attachment and is likely to play an important role in the regulation of IEC survival PMID: 21673109
    8. characterization of the bmf gene locus; molecular basis of the generation of the 2 major isoforms of Bmf; provide evidence that Bmf can act as a sensor for stress that associates with the repression of the conventional CAP-dependent translation machinery PMID: 20706276
    9. Data show that hypoxic conditions inhibit anoikis and block expression of proapoptotic BH3-only family members Bim and Bmf in epithelial cells. PMID: 20861305
    10. Bmf is upregulated by PS-341 and has a crucial role in PS-341-mediated glioma cell death through JNK phosphorylation. PMID: 19267218
    11. Up or downregulation of Bmf isoforms may have a role in regulating growth and survival in B cells and leukemic B-CLL cells PMID: 14574334
    12. histone hyperacetylation may enhance ionizing radiation-induced death via activation of Bmf transcription, thereby implying Bmf as a key molecule for HDAC inhibitors (FK228 and CBHA)-mediated enhancing effect on IR-induced cell death PMID: 16830229
    13. Bmf is a central mediator of anoikis in mammary cells and a target of oncogenes that contribute to the progression of glandular epithelial tumors PMID: 17360431
    14. arsenic trioxide upregulated expression of Bmf, Noxa, and Bim. Silencing of Bmf, Noxa, and Bim significantly protected MM cells from ATO-induced apoptosis PMID: 18354037
    15. Our data indicate a synergistic role for both bim and Bmf in an apoptotic pathway leading to the clearance of Neisseria gonorrhoeae -infected cells. PMID: 19300516
    16. Bmf supports Bim in regulating cell death processes in response to many stimuli. Review. PMID: 19641506
    17. MicroRNA-221 targets Bmf in hepatocellular carcinoma and correlates with tumor multifocality. PMID: 19671867

    顯示更多

    收起更多

  • 蛋白家族:
    Bcl-2 family
  • 組織特異性:
    Isoform 1 is mainly expressed in B-lymphoid cells. Isoform 2 and isoform 3 are mainly expressed in B-CLL and normal B-cells.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 24132

    OMIM: 606266

    KEGG: hsa:90427

    STRING: 9606.ENSP00000346697

    UniGene: Hs.591104



主站蜘蛛池模板: 中文字幕无码精品三级在线电影| 性一交一乱一色一视频| 18处破外女出血在线| 国产成熟妇女性视频电影| 久久香蕉国产线看观看猫咪av| 真人性囗交69视频| 青青草国产午夜精品| 老汉色老汉首页a亚洲| aⅴ亚洲 日韩 色 图网站 播放 | 最近更新中文字幕| 亚洲欧美日韩久久精品| 亚洲亚洲人成无码网www| 欧美欧洲成本大片免费| 自拍性旺盛老熟女| 狂野av人人澡人人添| 久久俺也去丁香综合色| 丰满妇女强制高潮18xxxx| 成人无码www免费视频| 国产成人免费无码av在线播放| 免费人成黄页在线观看国产| 69综合精品国产二区无码| 色狠狠久久av五月综合| 粉嫩虎白女毛片人体| 国产精品极品在线拍| 欧美一区二区三区成人片在线| 青娱乐极品视觉盛宴av| 9l国产精品久久久久麻豆| 亚洲午夜精品久久久久久浪潮| 天干天干天啪啪夜爽爽av | 色八区人妻在线视频免费| 成人做爰69片免费看网站| www亚洲精品久久久| 日韩精品专区在线影院重磅| 成熟妇人a片免费看网站| 插插无码视频大全不卡网站| 黑人巨大无码中文字幕无码| 三级网站视频在在线播放 | 漂亮人妻洗澡被公强 日日躁| 国产人妻丰满熟妇嗷嗷叫 | 国产一区二区三区在线观看免费 | 欧美孕妇xxxx做受欧美88|