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  4. BLID Antibody

BLID Antibody

  • 中文名稱：
    BLID兔多克隆抗體
  • 貨號：
    CSB-PA818276ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA818276ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) BLID Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    BLID
  • 別名：
    BH3-like motif containing; cell death inducer antibody; BH3-like motif-containing cell death inducer antibody; BLID antibody; BLID_HUMAN antibody; BRCC2 antibody; breast cancer cell 2 antibody; Breast cancer cell protein 2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human BH3-like motif-containing cell death inducer protein (1-108AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Functions as a proapoptotic molecule through the caspase-dependent mitochondrial pathway of cell death.
  • 基因功能參考文獻：
    1. Results showed that the expression of BLID is frequently downregulated in non-small cell lung tumors and cell lines and inversely correlates with miR-575 expression. PMID: 25728273
    2. loss of BLID may contribute to the progression of intraductal proliferation lesions to breast cancer. PMID: 24532431
    3. BRCC2 functions as a novel tumor suppressor in breast cancer and may be a potential therapeutic target for breast cancer management. PMID: 23928696
    4. Frequent loss of the BLID gene is observed in early-onset breast cancer. PMID: 21846966
    5. Tag single nucleotide polymorphisms near the BLID and LOC399959 genes are not susceptibility loci for high myopia in the Chinese Han population. PMID: 21031016
    6. BLID upregulation resulting from a novel IGH translocation is associated with childhood B-Cell precursor acute lymphoblastic leukemia. PMID: 20544842
    7. BLID is a new binding partner of Bcl-X(L) and a significant prognostic factor in breast cancer PMID: 20400521
    8. BRCC2 is a novel BH3-like domain-containing protein which induces apoptosis in a caspase-dependent manner PMID: 15069058
    9. BLID gene is assigned to 11p24.1. PMID: 18940476
    10. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 19779542

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  • 亞細胞定位：
    Cytoplasm. Mitochondrion. Note=Lower abundance in mitochondrion than in cytoplasm.
  • 組織特異性：
    Ubiquitously expressed.
  • 數據庫鏈接：

    HGNC: 33495

    OMIM: 608853

    KEGG: hsa:414899

    STRING: 9606.ENSP00000453153

    UniGene: Hs.686109



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