在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

BATF2 Antibody

  • 中文名稱:
    BATF2兔多克隆抗體
  • 貨號:
    CSB-PA822685LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA822685LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA822685LA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) BATF2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    BATF2
  • 別名:
    BATF2Basic leucine zipper transcriptional factor ATF-like 2 antibody; B-ATF-2 antibody; Suppressor of AP-1 regulated by IFN antibody; SARI antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Basic leucine zipper transcriptional factor ATF-like 2 protein (1-189AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,BATF2 Antibody (CSB-PA822685LA01HU),的標記方式是Non-conjugated。對于BATF2 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA822685LB01HU BATF2 Antibody, HRP conjugated ELISA
    FITC CSB-PA822685LC01HU BATF2 Antibody, FITC conjugated
    Biotin CSB-PA822685LD01HU BATF2 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes. Selectively suppresses CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CCN1 and inhibits CCN1-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CCN1 promoter.
  • 基因功能參考文獻:
    1. BATF2 gene was modulated after treatment with zebularine and was a poor prognostic marker, since its low levels were correlated with relapse and a poor prognosis for medulloblastoma patients. PMID: 27785591
    2. Gain- and loss-of-function studies uncovered a role for Batf2 in myeloid differentiation in both murine and human systems. We thus demonstrate that chronic infection can deplete HSPCs and identify BATF2 as a mediator of infection-induced HSPC terminal differentiation PMID: 27926863
    3. Our findings expanded the understanding of the role of BATF2 in tumors, and also suggested a potential of using BATF2 as a therapeutic target to hinder bevacizumab induced epithelial-mesenchymal transition in glioblastoma. PMID: 28739720
    4. BATF2 may exert selective pressure on the recombination machinery via a repetitive motif-based mechanism for the maintenance of heterochromatin stability. PMID: 26977016
    5. Batf2 has a role in infectious diseases and cancer PMID: 26376615
    6. Results demonstrate that SARI is a novel target gene of glucocorticoid receptor, and the upregulation of SARI plays an important role in dexamethasone's killing effect on B lymphoma cells. PMID: 26808579
    7. Suggest that SARI might play an important role in the occurrence and development of prostate cancer. IFN-beta might inhibit the growth of prostate cancer and promote cellular apoptosis by inducing the expression of SARI. PMID: 26339361
    8. In conclusion, as a tumor suppressor, BATF2 serves as a prognostic biomarker of esophageal squamous cell carcinoma and it may be a potential therapeutic target for ESCC treatment. PMID: 26135942
    9. these findings indicate that BATF2 status could be served as a potential biomarker to predict prognosis in colorectal cancer PMID: 26022579
    10. these novel findings suggest that BATF2, a tumor suppressor gene, is a potent negative regulator of HGF/MET signaling in colorectal cancer PMID: 25762344
    11. BATF2 plays a tumor-suppressor role in the development of oral tongue squamous cell carcinoma and BATF2 may serve as a prognostic biomarker and potential therapeutic target for this disease. PMID: 24252932
    12. SARI expression may predict a poor prognosis in non-small cell lung patients, and SARI may serve as a prognostic biomarker and potential therapeutic target for lung cancer. PMID: 24133583
    13. MDA-7/IL-24 has a role in cancer-specific apoptosis through SARI induction PMID: 24282278
    14. Loss of SARI expression initiates epithelial-to-mesenchymal transition (EMT), which is visualized by repression of E-cadherin and up-regulation of vimentin in lung adenocarcinoma cell lines and in clinical lung adenocarcinoma specimens. PMID: 23049725
    15. BCR-ABL mediates the down-regulation of SARI mRNA expression in K562 cells. PMID: 21867603
    16. Data suggest that SARI as a potential therapeutic target in CML. PMID: 21892628
    17. Decreased expression of BATF2 is associated with hepatocellular carcinoma. PMID: 20473897
    18. Inhibition of AP-1 by SARI negatively regulates transformation progression mediated by CCN1. PMID: 20531301

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    BZIP family
  • 數據庫鏈接:

    HGNC: 25163

    OMIM: 614983

    KEGG: hsa:116071

    STRING: 9606.ENSP00000301887

    UniGene: Hs.124840



主站蜘蛛池模板: 亚洲欧美日本国产专区一区| 草草地址线路①屁屁影院成人 | 国产口爆吞精在线视频2020版| 久久精品欧美日韩精品| 国产av大陆精品一区二区三区| 国产免费二卡3卡四卡| 蜜桃视频无码区在线观看| 精品人伦一区二区三区潘金莲| 92国产精品午夜免费福利视频| 国产在线高清视频无码| 国产欧美精品区一区二区三区| 国产性生交xxxxx免费| 亚洲色大成网站www永久网站| 亚洲热无码av一区二区东京热av | 久久www色情成人免费| 国产精品福利2020久久| 疯狂的欧美乱大交| 国产精品久久久久av福利动漫| 色欲综合久久躁天天躁蜜桃| 强行征服邻居人妻淑敏| 香港aa三级久久三级| 男女性杂交内射妇女bbwxz| 国产亚洲熟妇在线视频| 国产高清国产精品国产专区| 国产成人久久精品77777综合| 精产国品一二三产区蘑菇视频| 日本护士xxxxhd少妇| 大黑人交xxxx18视频| 亚洲精品日韩一区二区电影| 神马午夜福利不卡片在线| 天堂在线.www天堂在线资源| 狠狠88综合久久久久综合网| 国产精品爱啪在线播放| 亚洲国产精品无码中文字| 欧美丰满熟妇xxxx性ppx人交| 精品一区二区三区东京热| 色欲天天天综合网| 好爽又高潮了毛片免费下载| 国产性生交xxxxx免费| 美女黄频视频大全免费的国内| 国产成人一区二区三区app|