在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

BAG5 Antibody

  • 中文名稱:
    BAG5兔多克隆抗體
  • 貨號:
    CSB-PA438344
  • 規格:
    ¥1100
  • 圖片:
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: A549 cells, Hela cells, 293T cells, Primary antibody: CSB-PA438344(BAG5 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    BAG family molecular chaperone regulator 5 antibody; BAG-5 antibody; BAG5 antibody; BAG5_HUMAN antibody; Bcl 2 associated athanogene 5 antibody; Bcl-2-associated athanogene 5 antibody; BCL2 associated athanogene 5 antibody; KIAA0873 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human BAG5
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:500-1:5000
    WB 1:500-1:2000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN. May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.
  • 基因功能參考文獻:
    1. BAG5 was found as a expression variability marker in an 8-cell human embryo. PMID: 26288249
    2. Subsequent BAG5 upregulation ameliorated the tumor-suppressive effects of miR-127-3p overexpression in epithelial ovarian cancer (EOC). In conclusion, miR-127-3p functions as a tumor suppressor in EOC, and its influence on EOC is directly through regulation of BAG5. PMID: 27571744
    3. High BAG5 expression is associated with pancreatic cancer. PMID: 27571739
    4. This study showed that BAG2 (Bcl-2 associated athanogene family protein 2) and BAG5 (Bcl-2-associated athanogene family protein 5) stabilise pathogenic ataxin3-80Q by inhibiting its ubiquitination. PMID: 25006867
    5. BAG5 protects against mitochondrial oxidative damage through regulating PINK1 degradation. PMID: 24475098
    6. BAG5 is a binding partners of LRRK2 and part of a complex that promotes clearance of Golgi-derived vesicles through the autophagy-lysosome system. PMID: 24510904
    7. Bag5 is overexpressed in prostate cancer and plays a role in endoplamic reticulum-stress induced apoptosis. Furthermore we have identified GRP78/BiP as a novel interaction partner of Bag5. PMID: 23448667
    8. BAG5 directly interacts with Parkin and stabilizes Parkin via the ubiquitin-mediated proteasomal pathway. PMID: 21131737
    9. A novel function for BAG5 as a modulator of CHIP E3 ubiquitin ligase activity with implications for CHIP-mediated regulation of alpha-syn oligomerization. PMID: 21358815
    10. We replicated the association of BCL2L11 and CASP9 with non-Hodgkin's lymphoma risk at the gene and SNP level, and identified novel associations with BCLAF1 and BAG5. PMID: 20855536
    11. Bcl-2-associated athanogene 5 (BAG5) is a negative regulator of both Hsp70 and parkin function that sensitizes dopaminergic neurons to injury-induced death. PMID: 15603737

    顯示更多

    收起更多

  • 數據庫鏈接:

    HGNC: 941

    OMIM: 603885

    KEGG: hsa:9529

    STRING: 9606.ENSP00000338814

    UniGene: Hs.5443



主站蜘蛛池模板: 亚洲午夜福利av一区二区无码| 亚洲国产色播av在线| 东京热久久综合久久88| 国产熟妇高潮叫床视频播放| 久国产精品人妻aⅴ| 欧美性xxxx极品hd欧美风情| 亚洲全部无码中文字幕| 亚洲国产av无码精品| 中文字幕在线观看| 亚洲国产精品无码7777一线| 亚洲综合久久成人a片| 国产精品va无码一区二区| 亚洲精品一区二区三区婷婷月| 国产a线视频播放| 成人午夜特黄aaaaa片男男| 大陆熟妇丰满多毛xxxx| 亚洲熟女精品中文字幕| 美国特级a毛片免费网站| 欧美大片aaaaa免费观看| 人妻熟妇乱又伦精品视频中文字幕| 国产成人一区二区三区在线观看 | 人妻内射一区二区在线视频| 中文字幕无码日韩专区| 无码av无码天堂资源网影音先锋 | 亚洲精品无码伊人久久| 在线观看免费人成视频| 无码精品一区二区三区在线| 伦理片午夜视频在线观看| 无码国产精品一区二区vr| 热re99久久精品国99热| 国产成人精品久久| 7m精品福利视频导航| 国产按头口爆吞精在线视频| 亚洲学生妹高清av| 日韩毛片在线视频x| 久久综合久久88中字幕文| av无码av不卡一区二区| 一本色道无码不卡在线观看| 亚洲国产精品久久久天堂麻豆宅男| 国产成人精品日本亚洲999| 中文无码伦av中文字幕|