在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. B4GAT1 Antibody, FITC conjugated

B4GAT1 Antibody, FITC conjugated

  • 中文名稱：
    B4GAT1兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA002499EC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) B4GAT1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    B4GAT1
  • 別名：
    B4GAT1; B3GNT1; B3GNT6; Beta-1,4-glucuronyltransferase 1; I-beta-1,3-N-acetylglucosaminyltransferase; iGnT; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; Poly-N-acetyllactosamine extension enzyme; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Beta-1,4-glucuronyltransferase 1 protein (161-415AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer, which is further elongated by LARGE1, during synthesis of phosphorylated O-mannosyl glycan. Phosphorylated O-mannosyl glycan is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Required for axon guidance; via its function in O-mannosylation of alpha-dystroglycan (DAG1).
  • 基因功能參考文獻：
    1. B4GAT1 is involved in the initiation of the LARGE-dependent repeating disaccharide that is necessary for extracellular matrix protein binding to O-mannosylated alpha-dystroglycan. PMID: 25279697
    2. report describes the first truncating mutation in B3GNT1 and confirms that this gene, which plays a role in alphaDG glycosylation, is a bona fide disease gene in Walker-Warburg syndrome PMID: 23877401
    3. These functional studies identify an important role of B3GNT1 in the synthesis of the uncharacterized laminin-binding glycan of alpha-dystroglycan and implicate B3GNT1 as a novel causative gene for Walker-Warburg syndrome. PMID: 23359570
    4. These results demonstrate that B3GNT1 and B4GALT1 physically associate in vitro and in cultured cells, providing insight into possible mechanisms for regulation of polyLacNAc production. PMID: 19261593
    5. These results identify a previously undescribed role of carbohydrate-dependent cell-basement membrane interaction in tumor suppression and its control by beta3GnT1 and LARGE. PMID: 19587235

    顯示更多

    收起更多

  • 相關疾病：
    Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A13 (MDDGA13)
  • 亞細胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 49 family
  • 組織特異性：
    In the adult, highly expressed in heart, brain, skeletal muscle and kidney and to a lesser extent in placenta, pancreas, spleen, prostate, testis, ovary, small intestine and colon. Very weak expression in lung, liver, thymus and peripheral blood leukocyte
  • 數據庫鏈接：

    HGNC: 15685

    OMIM: 605517

    KEGG: hsa:11041

    STRING: 9606.ENSP00000309096

    UniGene: Hs.8526



主站蜘蛛池模板： 亚洲综合网站精品一区二区| 国产精品成人久久久久久久| 人人澡人摸人人添| 狠狠躁夜夜躁人人爽蜜桃| 国产成人无码免费视频97| 中文字幕av无码人妻| 成人av无码国产在线观看 | 中文字幕精品亚洲无线码二区| 麻花豆传媒剧国产免费mv入口| 国产粗话肉麻对白在线播放| 亚洲综合欧美在线一区在线播放 | 在线精品亚洲一区二区| 国产高清在线精品二区| 99视频偷窥在线精品国自产拍| 免费观看18禁无遮挡真人网站| 无码国产玉足脚交极品播放| 啪一啪射一射插一插| 欧美日韩在线视频一区| 国产免国产免费| 人妻av无码系列专区移动可看| 精品服丝袜无码视频一区 | 女乱高潮久久久久久爽爽| 无码国产玉足脚交极品网站| 国产1卡2卡三卡四卡精品| 色悠久久久久久久综合网| 国产成人无码av在线播放dvd| 亚洲国产精品无码久久一线| 免费大片av手机看片不卡 | 老妇女性较大毛片| 国产免费一区二区三区免费视频| 啪啪后入内射日韩| 国产国拍精品av在线观看按摩| 搡8o老女人老妇人老熟| 青青草av一区二区三区| 中文人妻无码一区二区三区在线| 国产一卡二卡三卡四卡视频版| 天天综合网网欲色| 九九热线有精品视频| 99热久久精里都是精品6| 国产男女猛烈无遮挡a片漫画| 精品久久久久久久久久久国产字幕|