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  4. B4GALT5 Antibody

B4GALT5 Antibody

  • 中文名稱：
    B4GALT5兔多克隆抗體
  • 貨號：
    CSB-PA527356LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      All lanes: B4GALT5 antibody at 8µg/ml
      Lane 1: Mouse heart tissue
      Lane 2: Mouse liver tissue
      Lane 3: Mouse brain tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 46 kDa
      Observed band size: 46 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA527356LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA527356LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) B4GALT5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    B4GALT5
  • 別名：
    4-galactosyltransferase 5 antibody; 4-GalT II antibody; 4-GalTase 5 antibody; B4Gal T5 antibody; b4Gal-T5 antibody; B4galt5 antibody; B4GT5_HUMAN antibody; Beta 1 4 galactosyltransferase 5 antibody; Beta 1 4 galactosyltransferase V antibody; Beta 1 4 GalT II antibody; Beta 1 4 GalT IV antibody; Beta 1 4 GalTase 5 antibody; Beta-1 antibody; Beta-1,4-galactosyltransferase 5 antibody; Beta-1,4-GalT II antibody; Beta-1,4-GalTase 5 antibody; Beta4 GALT IV antibody; Beta4Gal T5 antibody; Beta4Gal-T5 antibody; Beta4GalT V antibody; gt V antibody; gtV antibody; MGC138470 antibody; UDP Gal:beta GlcNAc beta 1 4 galactosyltransferase 5 antibody; UDP Gal:betaGlcNAc beta 1 4 galactosyltransferase 5 antibody; UDP Gal:betaGlcNAc beta 1 4 galactosyltransferase polypeptide 5 antibody; UDP galactose:beta N acetylglucosamine beta 1 4 galactosyltransferase 5 antibody; UDP-Gal:beta-GlcNAc beta-1 antibody; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5 antibody; UDP-galactose:beta-N-acetylglucosamine beta-1 antibody; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Beta-1,4-galactosyltransferase 5 protein (101-388AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，B4GALT5 Antibody (CSB-PA527356LA01HU)，的標記方式是Non-conjugated。對于B4GALT5 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA527356LB01HU B4GALT5 Antibody, HRP conjugated ELISA
    FITC CSB-PA527356LC01HU B4GALT5 Antibody, FITC conjugated
    Biotin CSB-PA527356LD01HU B4GALT5 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation. Plays a role in the glycosylation of BMPR1A and regulation of its protein stability. Essential for extraembryonic development during early embryogenesis.
  • 基因功能參考文獻：
    1. 2.3-kb 5'-flanking region of the human beta-1,4-GalT V gene was cloned and the region -116/-18 relative to the transcription start site as that having promoter activity. PMID: 15263012
    2. B4GALT1 and B4GALT5, two members of B4GALT gene family, are involved in the development of multidrug resistance of human leukemia cells. PMID: 23744354
    3. The expression of the beta-1,4-GalT V gene has been shown to be regulated by transcription factors Sp1 and Ets-1 in cancer cells.(review) PMID: 22687727
    4. These data reveal a critical role of beta1,4GalT V in the self-renewal and tumorigenicity of glioma-initiating cells. PMID: 20417617
    5. Over-expression of beta-1,4-galactosyltransferase V increases the growth of astrocytoma cell line PMID: 12385586
    6. results suggest that GalT V functioned as a novel glioma growth activator and might represent a novel target in glioma therapy PMID: 16461357
    7. Ets-1 enhances expression of the beta-1,4-GalT V gene through activation of the Sp1 gene in cancer cells PMID: 17656364

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  • 亞細胞定位：
    Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Golgi apparatus.
  • 蛋白家族：
    Glycosyltransferase 7 family
  • 組織特異性：
    Ubiquitously expressed.
  • 數據庫鏈接：

    HGNC: 928

    OMIM: 604016

    KEGG: hsa:9334

    STRING: 9606.ENSP00000360776

    UniGene: Hs.370487



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