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  4. B3GNT6 Antibody
  • 中文名稱：
    B3GNT6兔多克隆抗體
  • 貨號：
    CSB-PA744392LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: K562 whole cell lysate, HT29 whole cell lysate
      All lanes: B3GNT6 antibody at 10µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 43, 30 kDa
      Observed band size: 43 kDa
    • IHC image of CSB-PA744392LA01HU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) B3GNT6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    B3GNT6
  • 別名：
    B3GNT6Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase antibody; EC 2.4.1.147 antibody; Core 3 synthase antibody; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 antibody; BGnT-6 antibody; Beta-1,3-Gn-T6 antibody; Beta-1,3-N-acetylglucosaminyltransferase 6 antibody; Beta3Gn-T6 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase protein (251-345AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，B3GNT6 Antibody (CSB-PA744392LA01HU)，的標(biāo)記方式是Non-conjugated。對于B3GNT6 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA744392LB01HU B3GNT6 Antibody, HRP conjugated ELISA
    FITC CSB-PA744392LC01HU B3GNT6 Antibody, FITC conjugated
    Biotin CSB-PA744392LD01HU B3GNT6 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins. Plays an important role in the synthesis of mucin-type O-glycans in digestive organs.
  • 基因功能參考文獻(xiàn)：
    1. expression was markedly down-regulated in gastric and colorectal carcinomas PMID: 15755813
    2. alpha2beta1 integrin acquired core3 O-glycans in cells expressing core3 synthase with decreased maturation of beta1 integrin, leading to decreased levels of the alpha2beta1 integrin complex PMID: 19395705
  • 亞細(xì)胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 31 family
  • 組織特異性：
    Present in stomach and colon (at protein level). Restricted in the stomach, colon and small intestine, where core 3 structure is present.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24141

    OMIM: 615315

    KEGG: hsa:192134

    STRING: 9606.ENSP00000435352

    UniGene: Hs.352622



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