在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. B3GALTL Antibody

B3GALTL Antibody

  • 中文名稱：
    B3GALTL兔多克隆抗體
  • 貨號：
    CSB-PA004623
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HepG2 cells using β-1,3-Gal-TL Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    B3GLCT
  • 別名：
    B3GLCT antibody; B3GALTL antibody; B3GTLBeta-1,3-glucosyltransferase antibody; Beta3Glc-T antibody; EC 2.4.1.- antibody; Beta 3-glucosyltransferase antibody; Beta-3-glycosyltransferase-like antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human β-1,3-Gal-TL.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.
  • 基因功能參考文獻：
    1. Studies indicate that Peters Plus syndrome is caused by mutations in beta 3-glucosyltransferase (B3GALTL). PMID: 27049305
    2. POFUT2 and B3GLCT mediate a noncanonical endoplasmic reticulum quality-control mechanism that recognizes folded thrombospondin type 1 repeats and stabilizes them by glycosylation. PMID: 25544610
    3. Mutations in the coding region of B3GALTL were identified in nine patients; six had a documented phenotype of classic Peters plus syndrome (PPS) and the remaining three had a clinical diagnosis of PPS with incomplete clinical documentation. PMID: 23889335
    4. a novel c.597-2 A>G splicing mutation within the B3GALTL gene in typical Peters-plus syndrome PMID: 23954224
    5. A novel homozygous c.597-2A>G mutation was identified in both patients with Peters plus syndrome harbouring a novel splice site mutation in the B3GALTL gene PMID: 22759511
    6. Vertebral defects in a patient with Peters plus syndrome and mutations in B3GALTL. PMID: 21671750
    7. The present report confirms the wide clinical spectrum of Peters plus syndrome, underlines the major clinical criteria of the syndrome and the major implication of B3GALTL gene in this condition. PMID: 21067481
    8. Novel B3GALTL mutation in Peters-plus Syndrome PMID: 19796186
    9. B3GTL is transcribed in a wide range of tissues and has conserved domains and motifs PMID: 12943678
    10. We report here the molecular cloning and characterization of a novel beta1,3-glucosyltransferase (beta3Glc-T) that synthesizes a Glcbeta1,3Fucalpha- structure on the TSR domain. PMID: 16899492
    11. Biallelic truncating mutations in the beta 1,3-galactosyltransferase-like gene (B3GALTL) in all 20 tested patients, showed that Peters Plus is a monogenic, primarily single-mutation syndrome. PMID: 16909395
    12. Peters Plus syndrome is a new congenital disorder of glycosylation and involves defective Omicron-glycosylation of thrombospondin type 1 repeats.( PMID: 18199743
    13. two new mutant alleles, c.459 + 1G > A and c.230insT, were identified and predicted to result in truncated protein products; data confirm an important role for B3GALTL in causing typical Peters Plus syndrome PMID: 18798333

    顯示更多

    收起更多

  • 相關疾病：
    Peters-plus syndrome (PPLS)
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 31 family
  • 組織特異性：
    Widely expressed, with highest levels in testis and uterus.
  • 數據庫鏈接：

    HGNC: 20207

    OMIM: 261540

    KEGG: hsa:145173

    STRING: 9606.ENSP00000343002

    UniGene: Hs.13205



主站蜘蛛池模板： 亚洲中文字幕无码中文| 国产综合精品| 强被迫伦姧惨叫人妻系列| 老汉老妇姓交视频| 92国产精品午夜福利无毒不卡| 久久精品国产99久久久| 日本中文字幕有码在线视频| 亚洲成熟女人毛毛耸耸多| 国产九九99久久99大香伊| 国产大量精品视频网站| 狠狠色婷婷久久综合频道毛片| 春色校园综合人妻av| 国产在线观看超清无码视频一区二区 | 成熟丰满熟妇高潮xxxxx视频 | 欧美高清freexxxx性| 国产精品久久久久久爽爽爽床戏| 国产台湾无码av片在线观看 | 国产高清在线精品一区下载 | 午夜性色吃奶添下面69影院| 舌头伸进去搅动好爽视频| 亚洲aⅴ天堂av天堂无码麻豆| 婷婷色香合缴缴情av第三区| 国产精品麻豆aⅴ人妻| 377人体粉嫩噜噜噜| 亚洲精品动漫免费二区| 中文字幕人妻av一区二区| 午夜无码国产理论在线| 亚洲中文字幕无码一区| 双腿张开被9个男人调教| 性欧美丰满熟妇xxxx性5| 波多野结衣办公室33分钟| 成人亚洲欧美成αⅴ人在线观看| 国产亚洲精品第一综合另类灬| 日韩精品无码不卡无码| 中文国产成人精品久久不卡| 成在人线av无码免观看麻豆| 久久精品国产只有精品66| 色婷婷香蕉在线一区二区| 亚洲色18禁成人网站www| 精品一区二区三区影院在线午夜| 国产精品无码午夜福利|