在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. B3GALTL Antibody

B3GALTL Antibody

  • 中文名稱：
    B3GALTL兔多克隆抗體
  • 貨號：
    CSB-PA004623
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HepG2 cells using β-1,3-Gal-TL Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    B3GLCT
  • 別名：
    B3GLCT antibody; B3GALTL antibody; B3GTLBeta-1,3-glucosyltransferase antibody; Beta3Glc-T antibody; EC 2.4.1.- antibody; Beta 3-glucosyltransferase antibody; Beta-3-glycosyltransferase-like antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human β-1,3-Gal-TL.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.
  • 基因功能參考文獻：
    1. Studies indicate that Peters Plus syndrome is caused by mutations in beta 3-glucosyltransferase (B3GALTL). PMID: 27049305
    2. POFUT2 and B3GLCT mediate a noncanonical endoplasmic reticulum quality-control mechanism that recognizes folded thrombospondin type 1 repeats and stabilizes them by glycosylation. PMID: 25544610
    3. Mutations in the coding region of B3GALTL were identified in nine patients; six had a documented phenotype of classic Peters plus syndrome (PPS) and the remaining three had a clinical diagnosis of PPS with incomplete clinical documentation. PMID: 23889335
    4. a novel c.597-2 A>G splicing mutation within the B3GALTL gene in typical Peters-plus syndrome PMID: 23954224
    5. A novel homozygous c.597-2A>G mutation was identified in both patients with Peters plus syndrome harbouring a novel splice site mutation in the B3GALTL gene PMID: 22759511
    6. Vertebral defects in a patient with Peters plus syndrome and mutations in B3GALTL. PMID: 21671750
    7. The present report confirms the wide clinical spectrum of Peters plus syndrome, underlines the major clinical criteria of the syndrome and the major implication of B3GALTL gene in this condition. PMID: 21067481
    8. Novel B3GALTL mutation in Peters-plus Syndrome PMID: 19796186
    9. B3GTL is transcribed in a wide range of tissues and has conserved domains and motifs PMID: 12943678
    10. We report here the molecular cloning and characterization of a novel beta1,3-glucosyltransferase (beta3Glc-T) that synthesizes a Glcbeta1,3Fucalpha- structure on the TSR domain. PMID: 16899492
    11. Biallelic truncating mutations in the beta 1,3-galactosyltransferase-like gene (B3GALTL) in all 20 tested patients, showed that Peters Plus is a monogenic, primarily single-mutation syndrome. PMID: 16909395
    12. Peters Plus syndrome is a new congenital disorder of glycosylation and involves defective Omicron-glycosylation of thrombospondin type 1 repeats.( PMID: 18199743
    13. two new mutant alleles, c.459 + 1G > A and c.230insT, were identified and predicted to result in truncated protein products; data confirm an important role for B3GALTL in causing typical Peters Plus syndrome PMID: 18798333

    顯示更多

    收起更多

  • 相關疾病：
    Peters-plus syndrome (PPLS)
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 31 family
  • 組織特異性：
    Widely expressed, with highest levels in testis and uterus.
  • 數據庫鏈接：

    HGNC: 20207

    OMIM: 261540

    KEGG: hsa:145173

    STRING: 9606.ENSP00000343002

    UniGene: Hs.13205



主站蜘蛛池模板： 成 人色 网 站 欧美大片在线观看| 色狠狠成人综合网| 性生交大全免费看| 亚洲综合av色婷婷| 国产成人av无码永久免费一线天 | 欧美人与动牲交a精品| 日日摸天天摸爽爽狠狠97| 成视频年人黄网站视频福利| 国产午夜福利小视频合集| 亚洲最大成人网站| 麻豆国产97在线 | 欧美| 亚洲综合最新无码2020av| 国产成人午夜精品影院| 偷偷色噜狠狠狠狠的777米奇| 亚洲欧美综合区丁香五月小说| 亚洲乱码av一区二区| 久久久久人妻一区精品果冻| 国产小呦泬泬99精品| 羞羞视频在线观看| 国产最新精品自产在线观看| 久久精晶国产99久久6| 精品无码国产污污污免费网站| 国产精品无码日韩欧| 人人妻人人爽日日人人| 长腿校花无力呻吟娇喘的视频 | 无码熟妇人妻av在线电影| 亚洲精品一区二区三区蜜臀| 欧美性色大片在线观看| 骚动漫十八禁在线观看| 久久综合久久久久88| 西西人体大胆4444www| 亚洲中文无码永久免| 日本精品高清一区二区| 亚洲日本中文字幕天天更新| 午夜成人无码片在线观看影院| 色婷婷av一区二区三区浪潮| 婷婷四房播播| 爱色精品视频一区二区| av人摸人人人澡人人超碰手机版| 香港三日本三级少妇三级66| 丰满岳乱妇在线观看中字|