在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Aif1 Antibody, HRP conjugated

  • 中文名稱:
    Aif1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA001490HB01MO
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Mus musculus (Mouse) Aif1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    Aif1
  • 別名:
    Aif1 antibody; Iba1Allograft inflammatory factor 1 antibody; AIF-1 antibody; Ionized calcium-binding adapter molecule 1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Mouse
  • 免疫原:
    Recombinant Mouse Allograft inflammatory factor 1 protein (2-147AA)
  • 免疫原種屬:
    Mus musculus (Mouse)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
  • 基因功能參考文獻:
    1. Aif1 is important for bacterial and particle transcytosis in M cells. PMID: 28224999
    2. These findings indicate that the expression of AIF-1 in macrophages is critical for the activation of renal fibroblasts to a profibrotic phenotype. PMID: 29749461
    3. Macrophage-derived AIF-1 up-regulated reactive oxygen species production, adipokine TNFalpha, IL6, resistin release, and inhibited adiponectin secretion. PMID: 29788012
    4. A new subset of resident macrophages in the intestinal muscularis externa was discovered, identified as iba1(pos) CD169(neg). PMID: 27860408
    5. These results suggest that AIF-1 plays an important role in the mechanism underlying lung fibrosis, and may provide an attractive new therapeutic target. PMID: 29225172
    6. AIF-1 plays an important role in the mechanism underlying acute lung injury. PMID: 26911661
    7. These results imply daintain/AIF-1 triggers type 1 diabetes probably via arousing immune cells activation and induction of NO production in pancreas of NOD mice. PMID: 23022189
    8. AIF-1 was overexpressed in the liver of BALB/c mice infected with S. japonicum, and the interaction between AIF-1 and TNF-alpha or other cytokines played an important role in the pathogenesis and progression of hepatic schistosomiasis. PMID: 22150368
    9. Data suggest a strong association between AIF-1 expression, NF-kappaB activation, and development of experimental atherosclerosis. PMID: 21862018
    10. AIF-1 can induce IL-6 secretion on mononuclear cells and fibroblast chemotaxis. AIF-1 may accordingly provide an attractive new target for antifibrotic therapy in SSc as well as Scl GVHD. PMID: 21040744
    11. interferon gamma inducable and macrophage restricted expression requires Pu.1 PMID: 11861656
    12. This study demonstrated for the first time that allograft inflammatory factor-1(AIF-1) was expressed in uterus, and a correlation between AIF-1 production and fetal resorption in mice. PMID: 14506935
    13. These data indicate that AIF-1 mediates atherogenesis-initiated signaling and activation of macrophages. PMID: 16291819
    14. The molecular conformational change induced by Ca(2+)-binding of Iba1 is different from that found in the classical EF-hand proteins, which demonstrates that Iba1 has an unique molecular switching mechanism dependent on Ca(2+)-binding. PMID: 17011575
    15. AIF-1/Iba1 can be regarded a "pan-macrophage marker" because, except for alveolar macrophages, all subpopulations of macrophages examined express AIF-1/Iba1. PMID: 17874251
    16. allograft inflammatory factor 1 (AIF-1) expression results in increased signal transduction, neointimal formation, and vascular smooth muscle cell proliferation in injured mouse carotid arteries. PMID: 17991871
    17. These results suggest that enhanced AIF-1 expression leads to augmented incorporation of degenerated LDL by macrophages and promotes development of atherosclerotic vasculopathy. PMID: 18204784
    18. Iba1 was heavily expressed in the VM-M2, VM-M3 and RAW cells, but was mostly undetectable in the VM-NM1 cells and the AC cells. These findings support the microglial/macrophage origin of the metastatic VM-M2, VM-M3 tumor cells. PMID: 18398829
    19. AIF-1 is expressed in endothelial cells, macrophages and T cells in systemic sclerosis (SSc). PMID: 16868985

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, phagocytic cup.
  • 組織特異性:
    Abundantly expressed in the testis, moderately in the spleen and lymph nodes and at low levels in the liver and thymus. Detected in macrophages.
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲精品成人无码中文毛片不卡| 国产在线乱子伦一区二区| 日韩一区二区三区无码人妻视频 | 国产一性一交一伦一a片| 爆爽久久久一区二区又大又黄又嫩| 丰满护士巨好爽好大乳| 国产精品99久久精品爆乳| 国产成人午夜福利在线观看| 乱人伦无码中文视频在线| 国产性夜夜春夜夜爽免费下载| 日韩精品一区二区三区色欲av| 蜜桃精品成人影片| 午夜成人爽爽爽视频在线观看 | 国产午夜鲁丝片av无码| 极品尤物一区二区三区| 欧美性欧美巨大黑白大战| 四库影院永久国产精品地址| 粗大的内捧猛烈进出视频| 久久综合九色综合欧美98| 色综合久久中文娱乐网| 性xxx欧美老妇5060.70| 国产精品扒开腿做爽爽爽a片唱戏| 国产乱码精品一区二区三区中文| 亚洲精品字幕| 国产超碰女人任你爽| 婷婷射精av这里只有精品| 三叶草欧洲码在线| 无码精品a∨在线观看无广告| a∨在线视频播放| 国产三级精品三级| 无码一区二区三区中文字幕| 九色精品国产成人综合网站| 国产精品无码专区第一页| av色综合久久天堂av色综合在| 不卡无码av一区二区三区| 亚洲中文字慕日产2021| 国内精品久久久久久久小说| 成人性生交大片免费看r老牛网站| 成人影院yy111111在线| 人妻无码中字在线a| 2019nv天堂香蕉在线观看|