在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

AZIN1 Antibody

  • 中文名稱:
    AZIN1兔多克隆抗體
  • 貨號:
    CSB-PA002484LA01HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: AZIN1 antibody at 4µg/ml
      Lane 1: Mouse liver tissue
      Lane 2: PC-3 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 50 kDa
      Observed band size: 50 kDa
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA002484LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA002484LA01HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) AZIN1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Antizyme inhibitor 1 antibody; AZI antibody; Azin1 antibody; AZIN1_HUMAN antibody; OAZI antibody; OAZIN antibody; ODC1L antibody; Ornithine decarboxylase antizyme inhibitor antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Antizyme inhibitor 1 protein (101-400AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產(chǎn)品,AZIN1 Antibody (CSB-PA002484LA01HU),的標記方式是Non-conjugated。對于AZIN1 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA002484LB01HU AZIN1 Antibody, HRP conjugated ELISA
    FITC CSB-PA002484LC01HU AZIN1 Antibody, FITC conjugated
    Biotin CSB-PA002484LD01HU AZIN1 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.
  • 基因功能參考文獻:
    1. Using high-resolution (1)H-NMR spectroscopy, we demonstrated that a long-looped quadruplex in the AZIN1 mRNA co-exists in salt-dependent equilibria with a hairpin structure. PMID: 30063205
    2. e in vivo experiment confirmed that this RNA editing confers higher capacity of tumor migration as well. In conclusion, antizyme inhibitor 1 RNA editing and its involvement in tumorigenesis of non-small-cell lung cancer pave a new way for potential clinical management of non-small-cell lung cancer. PMID: 28849733
    3. AzI1 fulfils an essential regulatory function in polyamine homeostasis and cell proliferation. PMID: 25813938
    4. Data show the the interplay between the enzyme ornithine decarboxylase (ODC) and two regulatory proteins: antizyme (Az) and inhibitor (AzIN). PMID: 26305948
    5. This study also suggests that highly expressed AZI may be partly responsible for increased ODC activity and cellular transformation. PMID: 15670771
    6. edited form has a stronger affinity to antizyme, and the resultant higher AZIN1 protein stability promotes cell proliferation through the neutralization of antizyme-mediated degradation of ornithine decarboxylase (ODC) and cyclin D1 PMID: 23291631
    7. minor allelic SNP variant in 12th exon of AZIN1 associated with slower rates of fibrosis progression favors expression of novel splice form, AZIN1 SV2, that inhibits expression of fibrogenic genes in hepatic stellate cells. PMID: 21837750
    8. AZ_95-176 is the minimal AZ peptide that is fully functioning in the binding of ODC and AZI and inhibition of their function. PMID: 21931692
    9. SNP rs2679757 in the AZIN1 gene is associated with the risk of HBV-related liver cirrhosis in Chinese patients. PMID: 21586232
    10. Decreased ornithine decarboxylase is associated with prostate cancer. PMID: 20215859

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Orn/Lys/Arg decarboxylase class-II family, ODC antizyme inhibitor subfamily
  • 組織特異性:
    Expressed in liver.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 16432

    OMIM: 607909

    KEGG: hsa:51582

    STRING: 9606.ENSP00000321507

    UniGene: Hs.459106



主站蜘蛛池模板: 影视先锋av资源噜噜| 情侣激情18内射骚话国产| 精品人无码一区二区三区| 成人无码一区二区三区| 亚洲女女女同性video| 久久综合久久自在自线精品自 | 一本一本久久a久久精品综合麻豆| 精品无码国产一区二区三区51安 | 男女做爰真人视频直播| 国产欧美va欧美va香蕉在线观看| 一二三四观看视频社区在线| 中文字幕中文乱码www| 人妻丰满被色诱中文字幕| 亚洲日韩成人性av网站| 亚洲熟妇av一区二区三区浪潮| 亚洲成av人片在线观看无| 日本被黑人强伦姧人妻完整版| 国产96在线 | 韩国| 国产亚洲视频在线观看网址| 精品人妻少妇一区二区| 久久精品中文字幕一区二区三区| 成人无码男男gv在线观看网站| 成码无人av片在线电影网站| 黄网在线观看免费网站| 国产成人麻豆精品午夜福利在线| 无码国模大尺度视频在线观看| 国产真实伦在线观看| 艳妇乳肉豪妇荡乳av无码福利| 18禁黄网站禁片无遮挡观看| 免费观看又色又爽又湿的视频 | 任我撸在线视频| 日本精品αv中文字幕| 成人无码一区二区三区网站| 1000部拍拍拍18勿入免费视频下载 | 中文字幕精品一区二区2021年 | 亚洲欧美中文日韩v日本| 国产亚洲精品久久久久久彩霞| 亚洲日韩久久综合中文字幕| 护士的小嫩嫩好紧好爽| 日韩视频无码免费一区=区三区 | 粉嫩少妇内射浓精videos|