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Your Good Partner in Biology Research

AVIL Antibody

  • 中文名稱:
    AVIL兔多克隆抗體
  • 貨號:
    CSB-PA002464GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    AVIL
  • 別名:
    Actin binding protein DOC 6 antibody; Actin binding protein DOC6 antibody; Advil antibody; Advillin antibody; AVIL antibody; AVIL_HUMAN antibody; DOC 6 antibody; DOC6 antibody; p92 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Human AVIL
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Ca(2+)-regulated actin-binding protein which plays an important role in actin bundling. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis. In podocytes, controls lamellipodia formation through the regulation of EGF-induced diacylglycerol generation by PLCE1 and ARP2/3 complex assembly.
  • 基因功能參考文獻:
    1. NMR structure of the C-terminal headpiece subdomains of advillin. Evaluation of F-actin-binding requirements. PMID: 15096633
    2. Predicting the effect of a point mutation on a protein fold: the villin and advillin headpieces and their Pro62Ala mutants. PMID: 18022635
  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell junction, focal adhesion. Cell projection, neuron projection. Cell projection, axon.
  • 蛋白家族:
    Villin/gelsolin family
  • 組織特異性:
    Most highly expressed in the small intestine and colonic lining. Weaker expression also detected in the thymus, prostate, testes and uterus. Expressed in podocytes (at protein level).
  • 數據庫鏈接:

    HGNC: 14188

    OMIM: 613397

    KEGG: hsa:10677

    STRING: 9606.ENSP00000257861

    UniGene: Hs.584854



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