在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ATP6V0A4 Antibody

  • 中文名稱:
    ATP6V0A4兔多克隆抗體
  • 貨號:
    CSB-PA881016ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA881016ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA881016ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ATP6V0A4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    ATP6V0A4 antibody; ATP6N1B antibody; ATP6N2 antibody; V-type proton ATPase 116 kDa subunit a isoform 4 antibody; V-ATPase 116 kDa isoform a4 antibody; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4 antibody; Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human V-type proton ATPase 116 kDa subunit a isoform 4 protein (1-280AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney.
  • 基因功能參考文獻:
    1. The p. P137S and p. R302W mutations in ATP6V1B1 and p. S473F and p. R807X in ATP6V0A4, were novel disease-causing mutations of distal renal tubular acidosis. PMID: 30230413
    2. Distal renal acidosis patient carries two novel mutations, one in each of the genes ATP6V0A4 and ATP6V1B1. PMID: 29024829
    3. The aim of this work was to analyze the prevalence of genetic defects in SLC4A1, ATP6V0A4, and ATP6V1B1 genes and to assess the clinical phenotype of distal renal tubular acidosis patients that are eventually typical of the different genetic forms of the disease. PMID: 28233610
    4. ITM2A expression is positively regulated by PKA-CREB signaling and ITM2A expression interferes with autophagic flux by interacting with vacuolar ATPase. PMID: 25951193
    5. e have described patients with severe distal renal tubular acidosis and a novel splicing mutation in the ATP6V0A4 gene in a family originating from the Siliana region in northwestern Tunisia PMID: 25572248
    6. For the remaining patients, two mutations in the ATP6V0A4 gene, one of them being novel, were found in three Tunisian cases. PMID: 25285676
    7. Two from different families carrying ATP6V0A4 mutations manifested early onset moderate mixed HL and moderate SNHL PMID: 24975934
    8. Mutations of the ATP6V0A4 gene is associated with primary distal renal tubular acidosis. PMID: 23729491
    9. Case Report: novel ATP6V0A4 gene mutation confirmed autosomal recessive distal renal tubular acidosis with normal hearing. PMID: 22854161
    10. Four mutations in the ATP6V0A4 gene were obesrved one single nucleotide deletion in exon 13, the nonsensein exon 3, and the missense changes in exon 17 and in exon 19. PMID: 24252324
    11. This study demonistrated that expression identifies subtypes of oligodendrogliomas, pilocytic astrocytomas and gangliogliomas and may contribute to refine characterization of these tumors. PMID: 22460948
    12. There is the first evidence presented with progressive hearing loss associated with ATP6VOA4 mutation in a chinese patient. PMID: 22093743
    13. Novel compound heterozygous ATP6V0A4 mutations in an infant with distal renal tubular acidosis. PMID: 20221774
    14. stability and function of the metabolon composed of H+ATPase and glycolytic components can be compromised by either loss of required PFK-1 binding (G820R) or loss of pump protein (R807Q) PMID: 18632794
    15. the a4 isoform may be responsible for targeting V-ATPases to the plasma membrane of MB231 cells and that cell surface V-ATPases play a significant role in breast cancer invasion PMID: 19366680
    16. Mutations in ATP6V0A4 present enlarged vestibular aqueduct and early onset sensorial hearing loss. PMID: 19639346

    顯示更多

    收起更多

  • 相關疾病:
    Renal tubular acidosis, distal, autosomal recessive (RTADR)
  • 亞細胞定位:
    Apical cell membrane; Multi-pass membrane protein. Note=Present at high density almost exclusively on the apical surface of alpha-intercalated cells in the cortical collecting ducts of the distal nephron.
  • 蛋白家族:
    V-ATPase 116 kDa subunit family
  • 組織特異性:
    Expressed in adult and fetal kidney. Found in the inner ear.
  • 數據庫鏈接:

    HGNC: 866

    OMIM: 602722

    KEGG: hsa:50617

    STRING: 9606.ENSP00000253856

    UniGene: Hs.98967



主站蜘蛛池模板: 射精区-区区三区| 天天做天天大爽天天爱| 上司揉捏人妻丰满双乳电影| 亚洲欧美人高清精品a∨| 国产精品成人午夜久久| 99精品欧美一区二区三区| 亚洲国产av无码精品无广告| 国产在线精品无码二区| 成人无码视频在线观看网址| 撕开奶罩揉吮奶头视频| 欧美性大战久久久久久| 综合激情久久综合激情| 影音先锋啪啪av资源网站| 强行糟蹋人妻hd中文| 久久国产avjust麻豆| 国产精品久久久久久无码五月 | 国产成人a区在线观看视频| 无码无套少妇毛多18pxxxx| 免费观看又色又爽又黄的崩锅| 欧美乱大交av片久久123| 国产av成人无码精品网站| 中文字幕人乱码中文| 欧美乱人伦人妻中文字幕| 特级无码毛片免费视频播放▽| 奇米四色7777中文字幕| 最近中文字幕mv在线视频看| 中文无码久久精品| 丰满多毛的大隂户视频| 国内高清久久久久久| 色综合a怡红院怡红院| 亚洲国产精品美女久久久久| 人人妻人人澡人人爽国产一区| 亚洲第一最快av网站| 国产精品无码av不卡顿| 国产成人午夜精华液| 少妇伦子伦情品无吗| 欧美乱码伦视频免费| 无码少妇一区二区三区视频| 少妇饥渴xxhd麻豆xxhd骆驼| 国产有奶水哺乳期无码avav| 中文字字幕在线乱码视频|