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ATP5F1 Antibody

  • 中文名稱:
    ATP5F1兔多克隆抗體
  • 貨號:
    CSB-PA020295
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of 3T3 cells using ATP5F1 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    AT5F1_HUMAN antibody; ATP synthase B chain mitochondrial antibody; ATP synthase subunit b antibody; ATP synthase subunit b mitochondrial antibody; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit b; antibody; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit b; isoform 1 antibody; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit B1 antibody; ATP5F1 antibody; ATPase subunit b antibody; Cell proliferation inducing protein 47 antibody; H+ ATP synthase subunit b antibody; MGC24431 antibody; mitochondrial antibody; PIG47 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human ATP5F1.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
  • 基因功能參考文獻:
    1. Down-regulation of mitochondrial ATPase by hypermethylation mechanism in chronic myeloid leukemia is associated with multidrug resistance. PMID: 20038517
    2. Nitration of tyrosine residues 368 and 345 in the beta-subunit elicits FoF1-ATPase activity loss. PMID: 19650768
  • 亞細胞定位:
    Mitochondrion. Mitochondrion inner membrane.
  • 蛋白家族:
    Eukaryotic ATPase B chain family
  • 數據庫鏈接:

    HGNC: 840

    OMIM: 603270

    KEGG: hsa:515

    STRING: 9606.ENSP00000358737

    UniGene: Hs.514870



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