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ATG101 Antibody

  • 中文名稱：
    ATG101兔多克隆抗體
  • 貨號：
    CSB-PA883590LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of A549 cells with CSB-PA883590LA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ATG101 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    ATG101 antibody; Atg13-interacting protein antibody; ATGA1_HUMAN antibody; Autophagy-related protein 101 antibody; C12orf44 antibody; Chromosome 12 open reading frame 44 antibody; FLJ11773 antibody; OTTHUMP00000241687 antibody; OTTHUMP00000241688 antibody; OTTHUMP00000241689 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Autophagy-related protein 101 protein (1-218AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，ATG101 Antibody (CSB-PA883590LA01HU)，的標記方式是Non-conjugated。對于ATG101 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA883590LB01HU ATG101 Antibody, HRP conjugated ELISA
    FITC CSB-PA883590LC01HU ATG101 Antibody, FITC conjugated
    Biotin CSB-PA883590LD01HU ATG101 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation.
  • 基因功能參考文獻：
    1. Structure of the human Atg13-Atg101 HORMA heterodimer in the ULK1 complex that controls autophagy has been described. PMID: 26299944
    2. Data indicate mitogen lacritin stimulates FOXO3-ATG101 and FOXO1-ATG7 autophagic coupling and restores metabolic homeostasis. PMID: 23640897
    3. The identification of the novel protein, Atg101, and the validation of Atg13 and Atg101 as ULK1-interacting proteins, suggests an Atg1 complex is involved in the induction of macroautophagy in mammalian cells. PMID: 19287211
    4. These data suggest that Atg101 is a novel Atg protein that functions together with ULK, Atg13 and FIP200. PMID: 19597335
  • 亞細胞定位：
    Cytoplasm. Preautophagosomal structure.
  • 蛋白家族：
    ATG101 family
  • 數據庫鏈接：

    HGNC: 25679

    OMIM: 615089

    KEGG: hsa:60673

    STRING: 9606.ENSP00000338990

    UniGene: Hs.9911



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