在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ASTN2 Antibody, HRP conjugated

  • 中文名稱:
    ASTN2兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA002252LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ASTN2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Astn2 antibody; ASTN2_HUMAN antibody; Astrotactin 2 antibody; Astrotactin-2 antibody; bA264C15.1 antibody; bA67K19.1 antibody; KIAA0634 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Astrotactin-2 protein (108-272AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1. Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref.6).
  • 基因功能參考文獻:
    1. ASTN2 localizes primarily to endocytic and autophagocytic vesicles in the cell soma and in subsets of dendritic spines PMID: 30242134
    2. Our study suggests that the MEF2D, PRDM16 and ASTN2 genes from GWAS are associated with migraine susceptibility, especially migraine without aura , among Chinese patients. It appears that there is no association with serotonin receptor related genes. PMID: 28058730
    3. The findings of this study do not support a major role of ASTN2 variants in ADHD or its comorbid disorders respective aADHD associated personality traits. PMID: 27138430
    4. Results present the structure of ASTN-2 consisting of a combination of polypeptide folds: a perforin-like domain, a minimal epidermal growth factor-like module, a unique form of fibronectin type III domain and an annexin-like domain. Structural and biophysical data show that ASTN-2 binds inositol triphosphates, suggesting a mechanism for membrane recognition or secondary messenger regulation of its activity. PMID: 27249642
    5. The expression of coding and non-coding genes with SAFB1 cross-link sites was altered by SAFB1 knockdown. The isoform-specific expression of neural cell adhesion molecule (NCAM1) and ASTN2 was influenced by SAFB1. PMID: 26694817
    6. Study found a significant association of ASTN2 genetic variants with age at onset in Alzheimer's disease in two independent samples together with in silico analysis that demonstrated potential role of ASTN2 in the pathogenesis of the disease PMID: 25410587
    7. rs4836732 may contribute to hip OA susceptibility by altering proximal femur shape. PMID: 25939412
    8. 3' terminal ASTN2 deletions are significantly enriched in males with neurodevelopmental disorders, but not in females. PMID: 24381304
    9. Single nucleotide polymorphism in ASTN2 gene is associated with cognition disorders. PMID: 22504421
    10. Clinical trial and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20195266

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Multi-pass membrane protein. Perikaryon. Cytoplasm, cell cortex. Early endosome. Late endosome. Cytoplasmic vesicle, clathrin-coated vesicle. Cytoplasmic vesicle.
  • 蛋白家族:
    Astrotactin family
  • 數據庫鏈接:

    HGNC: 17021

    OMIM: 612856

    KEGG: hsa:23245

    STRING: 9606.ENSP00000354504

    UniGene: Hs.601562



主站蜘蛛池模板: 国产精品久久国产三级国不卡顿| 欧美成人一区二免费视频| 国产日韩欧美久久久精品图片| 99久久无码一区人妻a黑| 国产ktv交换配乱婬视频| 国产又黄又湿无遮挡免费视频| 国产精品99久久久久久久女警| 欧美激情性做爰免费视频| 亚欧美日韩香蕉在线播放视频| 免费国产h视频在线观看| 无码被窝影院午夜看片爽爽jk| 亚洲国产精品福利片在线观看| 久久久久久九九99精品| 超碰色偷偷男人的天堂| 一本久久伊人热热精品中文字幕| 强奷妇系列中文字幕| 中文无码乱人伦中文视频在线v| 色综合av综合无码综合网站| 波多老师无码av中字专区| 好疼太大了太粗太长了视频| 亚洲 欧美 中文 在线 视频| 国产高清成人免费视频在线观看| 国产精品无码素人福利| 色惰日本视频网站www| 日韩av片无码一区二区不卡电影| 波多野结衣50连登视频| 白丝乳交内射一二三区| 国产精品区一区二区三在线播放| 亚洲中文字幕无码一区| 国精产品999国精产| 麻豆精产一二三产区| 欧美精欧美乱码一二三四区 | 边啃奶头边躁狠狠躁| 冲田杏梨av一区二区三区| 人人妻人人妻人人人人妻人人| 狠狠噜天天噜日日噜| 久久久www成人免费精品| 日本黄漫动漫在线观看视频| 精品人伦一区二区三电影| 国产精品无码成人午夜电影| 满春阁精品a∨在线观看|