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ASCC2 Antibody

  • 中文名稱:
    ASCC2兔多克隆抗體
  • 貨號:
    CSB-PA296823
  • 規格:
    ¥1100
  • 圖片:
    • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-3: 293T cells, A431 cells, hepG2 cells, Primary antibody: CSB-PA296823(ASCC2 Antibody) at dilution 1/367, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    ASCC2
  • 別名:
    1700011I11Rik antibody; 2610034L15Rik antibody; Activating signal cointegrator 1 complex subunit 2 antibody; AI482016 antibody; ASC 1 complex subunit p100 antibody; ASC-1 complex subunit p100 antibody; ASC1P100 antibody; ASCC 2 antibody; Ascc2 antibody; ASCC2_HUMAN antibody; AW046480 antibody; FLJ21588 antibody; OTTMUSP00000005258 antibody; p100 antibody; RGD1561422 antibody; RP23-280J3.3 antibody; Trip4 complex subunit p100 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthetic peptide of Human ASCC2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. Involved in activation of the ribosome quality control (RQC) pathway, a pathway that degrades nascent peptide chains during problematic translation. As part of the ribosome quality control trigger (RQT) complex, recognizes ZNF598-dependent ubiquitination of stalled ribosomes.
  • 亞細胞定位:
    Nucleus. Nucleus speckle.
  • 蛋白家族:
    ASCC2 family
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 24103

    OMIM: 614216

    KEGG: hsa:84164

    STRING: 9606.ENSP00000305502

    UniGene: Hs.731754



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