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ARRDC1 Antibody

  • 中文名稱:
    ARRDC1兔多克隆抗體
  • 貨號:
    CSB-PA000933
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of Jurkat cells using Arrdc1 Polyclonal Antibody
    • Western Blot analysis of AD293 cells using Arrdc1 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    ARRDC1
  • 別名:
    ARRD1_HUMAN antibody; ARRDC 1 antibody; ARRDC1 antibody; Arrestin domain containing 1 antibody; Arrestin domain containing protein 1 antibody; Arrestin domain-containing protein 1 antibody; MGC40555 antibody; OTTHUMP00000022707 antibody; OTTHUMP00000022709 antibody; RP11-48C7.5 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human Arrdc1.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates. Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles. More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles. By participating in the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway.
  • 基因功能參考文獻:
    1. The authors show that WWP1 changes the ubiquitination status of ARRDC1, suggesting that the arrestins may provide a platform for ubiquitination in PPXY-dependent budding. PMID: 21191027
  • 亞細胞定位:
    Cell membrane.
  • 蛋白家族:
    Arrestin family
  • 數據庫鏈接:

    HGNC: 28633

    KEGG: hsa:92714

    STRING: 9606.ENSP00000360475

    UniGene: Hs.12999



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