在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ARR3 Antibody

  • 中文名稱:
    ARR3兔多克隆抗體
  • 貨號(hào):
    CSB-PA009894
  • 規(guī)格:
    ¥1090
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    ARR3
  • 別名:
    ARR3 antibody; ARR4 antibody; ARRC_HUMAN antibody; Arrestin 3 retinal antibody; Arrestin 3 retinal (X-arrestin) antibody; Arrestin 4 antibody; Arrestin-C antibody; ARRX antibody; C arrestin antibody; C-arrestin antibody; CAR antibody; cArr antibody; Cone arrestin antibody; Retinal cone arrestin 3 antibody; Retinal cone arrestin-3 antibody; X arrestin antibody; X-arrestin antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the C-terminal region of Human Arrestin-C.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    WB, IHC, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:5000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins.
  • 基因功能參考文獻(xiàn):
    1. These data suggest that heterozygous mutations in ARR3 might be responsible for X-linked female-limited early onset high myopia in the three families, a pattern contrary to the standard X-linked recessive trait. PMID: 27829781
    2. In the cell membrane, arrestin-3 dissociates quickly and almost completely from the Beta2-adrenoceptor. PMID: 25425623
    3. Identification of receptor binding-induced conformational changes in non-visual arrestins. PMID: 24867953
    4. The 25-amino acid N-domain element of arrestin 3 has the highest affinity for JNK3alpha2, suggesting that it is the key site for JNK3alpha2 docking. PMID: 24412749
    5. arrestin-3 regulates the activity of multiple JNK isoforms, suggesting that it might play a role in survival and apoptosis of all cell types. PMID: 24292834
    6. Silent scaffolds: inhibition OF c-Jun N-terminal kinase 3 activity in cell by dominant-negative arrestin-3 mutant. PMID: 22523077
    7. PP2A inhibits association between the Na+,K+-ATPase and arrestin, and diminishes the effect of arrestin on Na+,K+-ATPase trafficking. PMID: 22242112
    8. upon ligand activation, CysLT(1)R is tyrosine-phosphorylated and released from heterodimers with CysLT(2)R and, subsequently, internalizes from the plasma membrane to the nuclear membrane in a clathrin-, arrestin-3-, and Rab-5-dependent manner PMID: 21203429
    9. two non-visual arrestins, arrestin2 and arrestin3, localize to the centrosome, a key organelle involved in microtubule nucleation and bipolar mitotic spindle assembly PMID: 20056609
    10. Regulation of arrestin-3 phosphorylation by casein kinase II. PMID: 11877451
    11. The light-dependent translocation of cone arrestin suggests a role in light-dark adaptation of cones. PMID: 12824223
    12. association of arrestin-3 with the FSHR is dependent on receptor phosphorylation, however phosphorylation of the third intracellular loop residues is not needed for arrestin-3 association. PMID: 12850288
    13. Autoimmunity to this antigen and retinal vasculitis is not altered in patients with Behcet's disease PMID: 12918707
    14. Arrestin in all conformations binds JNK3 comparably, whereas Mdm2 preferentially binds cone arrestin 'frozen' in the basal state. PMID: 17680991
    15. Arrestin 3 but not arrestin 2 is required for internalization of C-C chemokine receptor CCR7 when bound to C-C chemokine ligand CCL19. In contrast, arrestins are not required for internalization of CCR7/CCL21. PMID: 18802075
    16. the molecular interactions of arrestin2 and arrestin3 and their individual domains with the components of the two MAPK cascades, ASK1-MKK4-JNK3 and c-Raf-1-MEK1-ERK2 PMID: 19001375

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment.
  • 蛋白家族:
    Arrestin family
  • 組織特異性:
    Inner and outer segments, and the inner plexiform regions of the retina.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 710

    OMIM: 301770

    KEGG: hsa:407

    STRING: 9606.ENSP00000311538

    UniGene: Hs.308



主站蜘蛛池模板: 色先锋资源久久综合5566| 亚洲午夜久久久影院伊人| 亚洲免费人成在线视频观看| 国产99视频精品免费视看9| 97色成人综合网站| 天天天天做夜夜夜做| 一本大道久久久久精品嫩草| 情欲少妇人妻100篇| 久久精品中文字幕大胸| 国内熟妇人妻色在线视频| 亚洲爆乳aaa无码专区| 凹凸在线无码免费视频| 97国产精东麻豆人妻电影| 亚 洲 成 人 网站在线观看| 成年无码动漫av片在线尤物网站| 40岁成熟女人牲交片20分钟| 欧美巨波霸乳影院| 天堂网www天堂在线资源| 亚洲自偷自拍另类12p| 亚洲熟妇无码爱v在线观看| 国产精品极品美女自在线观看免费| 四虎亚洲欧美成人网站| 中文字幕亂倫免賛視頻| 欧美性黑人极品hd| 老子午夜精品无码不卡| 无码一区18禁3d| 又色又爽又黄又无遮挡的网站| 18禁黄网站禁片免费观看| 亚洲欧美日韩久久精品| 337p日本欧洲亚洲大胆艺术图 | √天堂资源在线中文8在线最新版| 欧美巨大巨粗黑人性aaaaaa| 国产av精国产传媒| 亚洲aⅴ在线无码播放毛片一线天| 国产麻传媒精品国产av| 中文字幕乱码人妻一区二区三区| 女人被躁到高潮免费视频| 国产三级精品三级在线专区| 免费又黄又爽又色的视频| 大香伊蕉在人线国产网站首页| 欧美精品1卡二卡三卡四卡 |