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ARMC8 Antibody, HRP conjugated

  • 中文名稱:
    ARMC8兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA816877LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ARMC8 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ARMC8
  • 別名:
    Armadillo repeat containing protein 8 antibody; Armadillo repeat-containing protein 8 antibody; ARMC8 antibody; ARMC8_HUMAN antibody; HSPC056 antibody; MGC10058 antibody; MGC4880 antibody; S863 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Armadillo repeat-containing protein 8 protein (1-240AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.
  • 基因功能參考文獻:
    1. Knockdown of ARMC8 significantly inhibited osteosarcoma cell proliferation in vitro and markedly inhibited xenograft tumor growth in vivo. ARMC8 silencing also suppressed the epithelial-mesenchymal transition (EMT) phenotype, as well as inhibited the migration and invasion of osteosarcoma cells. PMID: 27712595
    2. results indicate that Armc8 may be a potential cancer marker in hepatocellular carcinoma PMID: 26944057
    3. invasiveness and migration capacity of HT29 cells transfected with ARMc8 were significantly greater than those of control cells (p < 0.001), while ARMc8 siRNA treatment significantly reduced cell invasion and migration in LoVo cells PMID: 26081621
    4. ARMc8 may enhance the invasion and metastasis of ovarian cancer cells PMID: 26232863
    5. Armc8 expression was elevated during atypia-to-carcinoma progression and associated with cancer development of breast carcinoma. PMID: 25119601
    6. Data suggest that armadillo repeat containing protein 8 (ARMC8) might serve as a therapeutic target in non-small cell lung cancer (NSCLC). PMID: 24894675

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  • 亞細胞定位:
    Nucleus. Cytoplasm.
  • 數據庫鏈接:

    HGNC: 24999

    KEGG: hsa:25852

    STRING: 9606.ENSP00000420333

    UniGene: Hs.744868



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