在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ARL6IP5 Antibody

  • 中文名稱:
    ARL6IP5兔多克隆抗體
  • 貨號:
    CSB-PA002096LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA002096LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA002096LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ARL6IP5 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ARL6IP5
  • 別名:
    ARL6IP5; DERP11; JWA; PRA2; PRAF3; HSPC127; PRA1 family protein 3; ADP-ribosylation factor-like protein 6-interacting protein 5; ARL-6-interacting protein 5; Aip-5; Cytoskeleton-related vitamin A-responsive protein; Dermal papilla-derived protein 11; GTRAP3-18; Glutamate transporter EAAC1-interacting protein; JM5; Prenylated Rab acceptor protein 2; Protein JWa; Putative MAPK-activating protein PM27
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human PRA1 family protein 3 protein (136-188AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,ARL6IP5 Antibody (CSB-PA002096LA01HU),的標記方式是Non-conjugated。對于ARL6IP5 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA002096LB01HU ARL6IP5 Antibody, HRP conjugated ELISA
    FITC CSB-PA002096LC01HU ARL6IP5 Antibody, FITC conjugated
    Biotin CSB-PA002096LD01HU ARL6IP5 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity-dependent manner. Plays a role in the retention of SLC1A1/EAAC1 in the endoplasmic reticulum.
  • 基因功能參考文獻:
    1. These data demonstrated that JWA suppressed the migration/invasion of breast carcinoma cells by downregulating the expression of CXCR4, and suggested that JWA may harbor prognostic and therapeutic potential in patients with breast cancer. PMID: 29658570
    2. increased RNF185 expression facilitated GC cell migration in vitro and promoted GC metastasis in vivo by downregulating JWA expression. PMID: 29481911
    3. our results demonstrate that JWA is a novel negative regulator of HER2 expression...in HER2-positive gastric cancer cells PMID: 27167206
    4. Protective effect of JWA against paraquat neurotoxicity involves regulation of the MEK/PI3K-Nrf2 axis. PMID: 28428137
    5. JWA and topoisomerase II alpha regulate each other in tumor cells arrested in G2/M. PMID: 26046674
    6. the JWA gene may regulate human breast cancer cells through the MAPK signaling pathway using different types of regulation. PMID: 25586271
    7. This review gives an overview of EAAC1-mediated GSH synthesis, and its regulatory mechanisms by GTRAP3-18 in the brain, and a potential approach against neurodegeneration. PMID: 23109897
    8. JWA reverses cisplatin resistance via the CK2-XRCC1 pathway in human gastric cancer cells. PMID: 25476899
    9. data demonstrate that JWA plays a crucial role in HCC progression and suggest JWA may be a potential prognostic biomarker and therapeutic target for HCC. PMID: 23169062
    10. A significant negative correlation between JWA and ILK in melanoma biopsies. PMID: 24064223
    11. Loss of JWA expression was strongly correlated with increased gastric cancer angiogenesis. PMID: 24072772
    12. JWA has an important role in ING4-regulated melanoma angiogenesis, and ING4/JWA/ILK are promising prognostic markers and may be used as anti-angiogenic therapeutic targets for melanoma. PMID: 24157826
    13. A combined effect of p53 with JWA as efficient prognostic indicators was found for the first time. PMID: 23285001
    14. JWA plays an important role in the occurrence and progress of human esophageal squamous cell carcinoma (ESCC) and that high expression level of JWA may predict a favorable prognosis in ESCC patients. PMID: 23461062
    15. JWA and XRCC1 protein levels were downregulated in gastric cancer lesions compared with adjacent noncancerous tissues;JWA and XRCC1 protein expressions in tumor are candidate prognostic markers and predictive factors for benefit from adjuvant platinum-based chemotherapy in resectable gastric carcinoma PMID: 22452940
    16. The gene polymorphisms at site 76 and GG/CT haploid type of JWA gene were associated with hypertension in workers exposed to high temperature. PMID: 22357531
    17. PRAF3 plays an important role in the regulation of tumor progression and metastasis and serves as a tumor suppressor in human ESCC. We propose that PRAF3 might be used as a potential therapeutic agent for human ESCC. PMID: 22433565
    18. JWA night play an important role in neoplastic transformation of HBE cells through regulation of p53 expression. PMID: 19080375
    19. all-trans retinoic acid increased JWA gene expression in human pulmonary artery smooth muscle cells. PMID: 16638297
    20. Rsults suggest that JWA can be regulated by oxidative stress and is actively involved in the signal pathways of oxidative stress in the cells. PMID: 15864752
    21. Data show that the JWA -76G-->C variant genotype may play an important role in transcription regulation of JWA gene and in the susceptibility to bladder cancer. PMID: 16331563
    22. JWA may function as a lineage-restricted gene during differentiation along the monocyte/macrophage-like or granulocytic pathway PMID: 16430862
    23. all-trans retinoic acid up-regulates JWA expression by stimulating the transcriptional activity of JWA gene promoter PMID: 16468075
    24. The JWA determined might function as a potential effective environmental responsive gene and actively participated in the process of B (a) P exposure associated with intracellular signal pathways of DNA damage and repair PMID: 16640902
    25. JWA participates in the signal pathways of H2O2 induced oxidative stress in K562 cells PMID: 16766476
    26. The effects of All Trans Retinoic Acid in regulating cellular proliferation and apoptosis may be mediated in part by JWA expression. PMID: 16922813
    27. JWA regulated-tumor cellular migration might involve MAPK cascades activation and F-actin cytoskeleton rearrangement mechanisms. PMID: 17336041
    28. Three novel functional genetic poly- morphisms of JWA gene, -76C, 454A, and 723G, appear to contribute to the etiology of bladder cancer PMID: 17479401
    29. Single nucleotide polymorphisms of JWA were associated with enhanced risk of gastric cancer and esophageal squamous cell carcinoma in a Chinese population. PMID: 17479402
    30. The potentially functional genetic polymorphism 454CA of the JWA gene appears to contribute to the risk of multiple kinds of leukemia in a south Chinese population. PMID: 17479403
    31. These results show GTRAP3-18 to negatively and dominantly regulate cellular GSH content via interaction with EAAC1 at the plasma membrane. PMID: 17646425
    32. Expression of GTRAP3-18 delays the ER exit of EAAC1, as well as other members of the excitatory amino acid transporter family. PMID: 18167356
    33. This paper deals primarily with PRAF2, but comparisons with PRAF3 are also provided. PMID: 16481131
    34. protein expression is upregulated by methyl-beta-cyclodextrin and not by retinoic acid PMID: 12562531
    35. highly conserved protein and genomic organization amongst vertebrates PMID: 12119102

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm. Cytoplasm, cytoskeleton.
  • 蛋白家族:
    PRA1 family
  • 數據庫鏈接:

    HGNC: 16937

    OMIM: 605709

    KEGG: hsa:10550

    STRING: 9606.ENSP00000273258

    UniGene: Hs.518060



主站蜘蛛池模板: 久久久久国产a免费观看rela| 国产明星裸体xxxx视频| 久草热久草热线频97精品| 色噜噜一区二区三区| 国产欧美另类久久精品蜜芽| 白嫩无码人妻丰满熟妇啪啪区百度| 高中生粉嫩无套第一次| 亚洲女人被黑人巨大进入| 亚洲性无码av在线欣赏网| 在线综合亚洲欧美网站| 国产果冻豆传媒麻婆精东| 51国产偷自视频区视频| 国产精品国产免费无码专区不卡| 精品亚洲国产成人蜜臀优播av| 国产女人叫床高潮大片| 成人欧美一区二区三区| 精品一区二区三区在线观看视频| 52熟女露脸国语对白视频| 亚洲国产色播av在线| 久久久精品午夜免费不卡| 呦男呦女视频精品八区| 18禁止观看强奷免费国产大片| 2019日韩中文字幕mv| 国内精品伊人久久久久7777| 亚洲精品你懂的在线观看| 久久av高潮av无码av| 欧美乱妇高清无乱码| 成人麻豆日韩在无码视频| 国产欧洲精品自在自线官方| 国产综合色在线精品| 亚洲 精品 综合 精品 自拍| 人妻人人澡人人添人人爽人人玩| 蜜桃少妇av久久久久久久| 日本免费大黄在线观看| 亚洲性av免费| 亚洲欧美中文字幕日韩一区二区 | 激情综合婷婷丁香五月情| 久久av高潮av无码av喷吹| 人人妻人人澡人人爽人人精品av| 成人无码男男gv在线观看网站| 国产高清在线精品一区下载 |