在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ARHGEF9 Antibody

  • 中文名稱:
    ARHGEF9兔多克隆抗體
  • 貨號(hào):
    CSB-PA008344
  • 規(guī)格:
    ¥1090
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    ARHGEF9
  • 別名:
    9630036L12Rik antibody; A230067K14 antibody; ARHG9_HUMAN antibody; Arhgef9 antibody; Cdc42 guanine nucleotide exchange factor (GEF) 9 antibody; Collybistin antibody; collybistin I antibody; EIEE8 antibody; HPEM 2 antibody; hPEM-2 collybistin antibody; KIAA0424 antibody; mKIAA0424 antibody; OTTHUMP00000023424 antibody; OTTHUMP00000023425 antibody; OTTHUMP00000023427 antibody; PEM 2 antibody; PEM 2 homolog antibody; PEM-2 homolog antibody; PEM2 antibody; Rac/Cdc42 guanine nucleotide exchange factor 9 antibody; Rho guanine nucleotide exchange factor 9 antibody; RP11 357C3.4 antibody; RP23 230K20.3 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the C-terminal region of Human ARHGEF9.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
  • 基因功能參考文獻(xiàn):
    1. Autism spectrum disorder patient with the smallest inactivating deletion in the collybistin gene. PMID: 27238888
    2. Collybistin forms a complex with mTOR and eIF3 and by sequestering these proteins downregulates mTORC1 signaling and protein synthesis potentially contributing to intellectual disability and autism. PMID: 25898924
    3. Impairment of the membrane lipid binding activity of Collybistin R290H and a consequent defect in inhibitory synapse maturation represent a likely molecular pathomechanism of epilepsy and mental retardation in humans. PMID: 25678704
    4. Data indicate that ARHGEF9 is likely to be responsible for syndromic X-linked mental retardation associated with epilepsy. PMID: 21633362
    5. These results reveal that G(s) and G(q) signalings regulate hPEM-2 functions through PKA and c-Src in Neuro-2a neuroblastoma cells, respectively. PMID: 22033413
    6. major regulator of GABAergic postsynaptic gephyrin clustering PMID: 21807943
    7. Here we identified residues critical for interaction with gephyrin in the linker region between the SH3 and the DH domains of collybistin. PMID: 11727829
    8. translocates gephyrin to submembrane microaggregates; collybistin mutation (G55A)is found in exon 2 of the ARHGEF9 gene in a patient with clinical symptoms of both hyperekplexia and epilepsy PMID: 15215304
    9. Results show that hPEM-2 is a target protein of Smurf1. PMID: 18208356

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Epileptic encephalopathy, early infantile, 8 (EIEE8)
  • 亞細(xì)胞定位:
    Cytoplasm. Cell junction, synapse, postsynaptic density.
  • 組織特異性:
    Detected in brain. Detected at low levels in heart.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 14561

    OMIM: 300429

    KEGG: hsa:23229

    STRING: 9606.ENSP00000253401

    UniGene: Hs.54697



主站蜘蛛池模板: 亚洲爆乳成av人在线视水卜| 亚洲精品白浆高清久久久久久| 亚洲2022国产成人精品无码区| 国产三区在线成人av| 中国人妻被两个老外三p| 中国国产1级毛卡片| 精品人伦一区二区三电影| 美女张开腿黄网站免费| 麻豆tv入口在线看| 无码手机线免费观看| 777米奇色狠狠俺去啦| 窝窝午夜看片| 99re热这里只有精品视频| 色欲色香天天天综合无码| 国内永久福利在线视频图片| 日本xxxx裸体xxxx视频大全| 欧美极品少妇×xxxbbb| 国内精品人妻无码久久久影院| 2020最新无码国产在线观看| 亚洲色中文字幕无码av| 久久国产欧美日韩精品| 久热国产vs视频在线观看| 美女视频黄的全免费视频网站| 国产精品毛片在线完整版sab| 国模小黎自慰gogo人体| 高清情侣国语自产拍| 午夜成人影院网站18进| 国产无套露脸在线观看| 亚洲三区在线观看无套内射 | 亚洲中文字幕在线无码一区二区| 色六月婷婷亚洲婷婷六月| 蜜臀avwww国产天堂| 欧美性xxxxx极品娇小| 亚洲伊人久久大香线蕉综合图片 | 97视频精品全国免费观看| 久久视热这里只有精品| 久久无码精品一区二区三区| 久久久精品中文字幕麻豆发布| 中文精品一卡2卡3卡4卡国色| 黄页网站视频免费大全| 国产人久久人人人人爽|