在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ARHGAP29 Antibody

ARHGAP29 Antibody

  • 中文名稱(chēng)：
    ARHGAP29兔多克隆抗體
  • 貨號(hào)：
    CSB-PA681475LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA681475LA01HU diluted at 1:200 and staining in paraffin-embedded mouse kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody
    • Immunofluorescence staining of U251 cell with CSB-PA681475LA01HU at 1:130, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • Immunofluorescence staining of U251 cell with 5% goat serum, counter-stained with DAPI. TheCcells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • Immunofluorescence staining of A431 cell with CSB-PA681475LA01HU at 1:130, counter-stained with DAPI. TheCcells wereCfixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • Immunofluorescence staining of U251 cell with CSB-PA681475LA01HU at 1:130, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) ARHGAP29 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ARHGAP29
  • 別名：
    ARHGAP 29 antibody; Arhgap29 antibody; ARHGAP29 protein antibody; MGC166097 antibody; PARG 1 antibody; PARG1 antibody; PTPL1 associated RhoGAP 1 antibody; PTPL1-associated RhoGAP protein 1 antibody; RHG29_HUMAN antibody; Rho GTPase activating protein 29 antibody; Rho GTPase activating protein 29 isoform CRA_a antibody; Rho GTPase activating protein 29 isoform CRA_b antibody; Rho GTPase-activating protein 29 antibody; Rho-type GTPase-activating protein 29 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Rho GTPase-activating protein 29 protein (161-392AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，ARHGAP29 Antibody (CSB-PA681475LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于ARHGAP29 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱(chēng) 應(yīng)用
    HRP CSB-PA681475LB01HU ARHGAP29 Antibody, HRP conjugated ELISA
    FITC CSB-PA681475LC01HU ARHGAP29 Antibody, FITC conjugated
    Biotin CSB-PA681475LD01HU ARHGAP29 Antibody, Biotin conjugated ELISA
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:100-1:200
    IF 1:50-1:150
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis.
  • 基因功能參考文獻(xiàn)：
    1. Risk haplotypes affect ARHGAP29 expression causing non-syndromic orofacial clefting. PMID: 28287101
    2. The variant in question segregates as an autosomal dominant trait caused by an heterozygous missense variant in ARHGAP29 (p.Ser552Pro) that had not previously been identified in a population genomic databases. The p.Ser552Pro ARHGAP29 variant was not present in genomic databases and was predicted to be pathogenic by multiple in silico programs. PMID: 28029220
    3. YAP promotes the expression of ARHGAP29 to suppress the RhoA-LIMK-cofilin pathway, destabilizing F-actin. PMID: 28538170
    4. The of loss-of-function and ARHGAP29 missense variants in the etiology of oral clefts PMID: 27350171
    5. Data indicate that through GTPase-activating proteins ArhGAP29 complex formation Rap1 GTP-binding protein spatially restricts Rho-mediated signaling, which is necessary for endothelial barrier potentiation. PMID: 25963656
    6. Genetic variants in ARHGAP29 contribute to the development of nonsyndromic cleft lip with cleft palate. PMID: 25163644
    7. We identified genetic variants in TGFB3 and ARHGAP29 associated with suboptimal healing outcome. PMID: 24635173
    8. Rasip1-ArhGAP29 pathway also functions in Rap1-mediated regulation of endothelial junctions, which controls endothelial barrier function PMID: 23798437
    9. ARHGAP29 is the etiologic gene for the cleft lip with or without cleft palate locus identified by genome-wide association on chromosome 1p22. PMID: 23008150
    10. PARG1 expression was substantially reduced & it displayed at least partial promoter methylation in all investigated mantle-cell lines & in 31 primary cases. PARG1 is a strong candidate tumor suppressor gene in MCL. PMID: 17488656

    顯示更多

    收起更多

  • 組織特異性：
    Widely expressed. Highly expressed in skeletal muscle and heart. Expressed at intermediate level in placenta, liver and pancreas. Weakly expressed in brain, lung and kidney.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 30207

    OMIM: 610496

    KEGG: hsa:9411

    STRING: 9606.ENSP00000260526

    UniGene: Hs.483238



主站蜘蛛池模板： 四虎成人精品国产永久免费无码| 日本三级在线播放线观看视频| 顶级少妇做爰视频在线观看 | 亚洲国产成人精品激情姿源| 中文字幕精品一二三四五六七八| 韩国精品一区二区无码视频| 西西人体大胆4444www| 国产乱人伦偷精品视频下| 无码专区—va亚洲v专区| 熟妇与小伙子matur老熟妇e | 日本强好片久久久久久aaa| 香蕉在线精品视频在线| 免费三级现频在线观看播放| 少妇被又大又粗又爽毛片久久黑人 | 白嫩少妇bbw撒尿视频| 在线观看老湿视频福利| 男女吃奶做爰猛烈紧视频 | 精品无码久久久久久国产| 亚洲成a人v欧美综合天堂下载| 人妻少妇88久久中文字幕| 一边吃奶一边添p好爽高清视频| 人妻无码一区二区三区四区| 精品人妻少妇嫩草av无码专区| 国产成人精品一区二区视频 | 国产成人小说视频在线观看| 欧美激情肉欲高潮视频| 亚洲卡1卡2卡新区网站| 久久久久国产精品人妻aⅴ四季| 免费极品av一视觉盛宴| 欧洲亚洲色一区二区色99| 国产真实野战在线视频| 欧美饥渴少妇xxxxx性| 国产精品宾馆在线精品酒店 | 亚洲人成在线影院| 久久精品国产福利一区二区| 少妇熟女久久综合网色欲| 亚洲第一无码xxxxxx| 成 人 色 网 站免费观看| 国产av成人精品播放| 综合自拍亚洲综合图区高清| 特大巨黑吊xxxx高潮|