在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ARHGAP18 Antibody

  • 中文名稱:
    ARHGAP18兔多克隆抗體
  • 貨號:
    CSB-PA002019GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    ARHGAP18
  • 別名:
    4833419J07Rik antibody; AI314906 antibody; AI843501 antibody; Arhgap18 antibody; bA307O14.2 antibody; FLJ25728 antibody; MacGAP antibody; MGC126757 antibody; MGC138145 antibody; OTTHUMP00000017190 antibody; OTTMUSP00000028606 antibody; RHG18_HUMAN antibody; Rho GTPase-activating protein 18 antibody; Rho-type GTPase-activating protein 18 antibody; SENEX antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human ARHGAP18
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state. Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1. Regulates cell shape, spreading, and migration.
  • 基因功能參考文獻(xiàn):
    1. Our data suggest that ARHGAP18, which was located by the SNP rs11759328 via positive selection, plays a potential role in regulating HbF expression in beta-thalassaemia and may be a promising therapeutic target PMID: 28983712
    2. these results define opposing roles for oncogenic ARHGAP18 and tumor suppressive miR-200b in determining triple-negative breast cancer cell migration and metastatic prowess PMID: 28619708
    3. data suggest the ARHGAP18 may confer vulnerability to SZ in the Chinese Han population, providing additional evidence for the involvement of neurodevelopmental dysfunction in the pathogenesis of schizophrenia PMID: 28384650
    4. In endothelial cells, ARHGAP18 may act as a significant regulator of vascular homeostasis. PMID: 28251925
    5. Our results show that miR-181a is down-regulated in glioblastoma multiforme (GBM) patients. The three target genes, ANGPT2, ARHGAP18 and LAMC1, are negatively correlated with the expression of miR-181a. Moreover, high expression of ANGPT2 or LAMC1 together with large size of GBM is correlated with a shorter median overall survival PMID: 27176932
    6. Results describe ARHGAP18 as a novel negative regulator of sprouting by acting dualistically to limit tip cell formation and to maintain junctional integrity. PMID: 25425145
    7. The results define ARHGAP18 as one of the crucial factors for the regulation of RhoA for the control of cell shape, spreading, and migration. PMID: 21865595
    8. identification of a novel gene, SENEX, that regulates stress induced premature senescence pathways in endothelial cells involving p16(INK4a) and retinoblastoma protein activation PMID: 20664062
    9. This study use Functional MRI and Genome Wide Association Analysis indentic novel gene(ARHGAP18) associated with schizophrenia. PMID: 19065146

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 21035

    OMIM: 613351

    KEGG: hsa:93663

    STRING: 9606.ENSP00000275189

    UniGene: Hs.486458



主站蜘蛛池模板: 日韩亚洲国产综合高清 | 成人午夜福利视频后入| 亚洲国产精品成人午夜在线观看| 成人亚洲精品久久久久软件| 亚洲区欧美区综合区自拍区| 国产福利酱国产一区二区| 欧美疯狂xxxxbbbb喷潮| 中日av乱码一区二区三区乱码| 亚洲国产成人久久综合碰| 老司机久久一区二区三区| 女人高潮抽搐潮喷小视频| 亚洲人成无码网站在线观看| 久久婷婷国产综合精品| 好男人社区www在线官网| 国产精品青青在线观看爽| 久久国产亚洲精品无码| 一本久道中文无码字幕av| 欧洲熟妇色xxxxx欧美老妇伦| 国产精品亚洲综合一区在线观看| 亚洲综合无码无在线观看| 极品人妻少妇一区二区三区| 热re99久久精品国99热| 国产成人精品高清在线观看99| 9久9久女女热精品视频在线观看 | 337p亚洲日本中国大胆69| 色八区人妻在线视频免费| 蜜臀av无码人妻精品| 特黄特级毛片免费视频| 亚洲婷婷五月激情综合app| 免费国产裸体美女视频全黄| 久久人搡人人玩人妻精品首页| 国产精品国语对白露脸在线播放| 国产欧美另类久久久精品不卡| 中文精品久久久久国产网址| 久久精品国产一区二区三区| 在线观看的av免费网站| 377人体粉嫩噜噜噜| 人妻丝袜中文无码av影音先锋专区| 久久精品国产久精国产果冻传媒| 国产美女久久久亚洲综合| 日日碰狠狠躁久久躁蜜桃|