在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ARHGAP17 Antibody

ARHGAP17 Antibody

  • 中文名稱：
    ARHGAP17兔多克隆抗體
  • 貨號：
    CSB-PA030179
  • 規格：
    ￥1090
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    ARHGAP17
  • 別名：
    ARHGAP17 antibody; RICH1 antibody; MSTP066 antibody; MSTP110 antibody; Rho GTPase-activating protein 17 antibody; Rho-type GTPase-activating protein 17 antibody; RhoGAP interacting with CIP4 homologs protein 1 antibody; RICH-1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human ARHGAP17.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.
  • 基因功能參考文獻：
    1. In vitro analysis demonstrated that ARHGAP17 overexpression inhibited cell growth and invasion of HCT-8 and HCT-116 cells. PMID: 29730655
    2. show that ARHGAP17 binds to the actin-regulating CIP4 protein in platelets and that Ser-702 phosphorylation interferes with this interaction PMID: 26507661
    3. Rich1 negatively regulates the epithelial cell cycle, proliferation and adhesion by CDC42/RAC1-PAK1-Erk1/2 pathway. PMID: 26004135
    4. We propose that Rich1 and Amot maintain TJ integrity by the coordinate regulation of Cdc42 and by linking specific components of the TJ to intracellular protein trafficking. PMID: 16678097
  • 亞細胞定位：
    Membrane; Peripheral membrane protein. Cytoplasm. Cell junction, tight junction. Note=Associates with membranes and concentrates at sites of cell-cell contact.
  • 組織特異性：
    Ubiquitously expressed. Expressed at higher level in heart and placenta.
  • 數據庫鏈接：

    HGNC: 18239

    OMIM: 608293

    KEGG: hsa:55114

    STRING: 9606.ENSP00000289968

    UniGene: Hs.373793



主站蜘蛛池模板： 在线观看国产丝袜控网站| 亚洲中文无码线在线观看| 国产精品99久久久久久宅男小说| 亚洲美女被黑人巨大在线播放| 漂亮人妻被中出中文字幕| 亚洲18禁私人影院| 国产综合久久久久| 精品亚洲国产成av人片传媒| 伊人精品一本久久综合| 亚洲在av人极品无码| 双腿高潮抽搐喷白浆视频| 午夜国产亚洲精品一区| 人与性动交aaaabbbb| 亚洲日韩va无码中文字幕| 免费毛片a线观看| 色猫咪免费人成网站在线观看| 性色av一区二区三区人妻| 18无码粉嫩小泬无套在线观看 | 免费两性的视频网站| 久青草国产97香蕉在线视频| 国外亚洲成av人片在线观看| 亚洲中文字幕无码中文字在线| 夜夜夜高潮夜夜爽夜夜爰爰| 亚洲 欧美 另类图片| 欧美国产日韩亚洲中文| 欧美综合在线激情专区| 日韩av影院在线观看| 欧美大黑帍在线播放| 饥渴丰满少妇大力进入| 夜夜香夜夜摸夜夜添视频| 蜜臀精品无码av在线播放| 欧美三级不卡在线观看| 亚洲中文久久精品无码照片| 丰满少妇aaaaaa爰片毛片| 亚洲综合色区中文字幕| 亚洲人成色4444在线观看| 四虎国产精亚洲一区久久特色| 久久精品人人做人人爽97| 久久久国产精品无码免费专区| 亚洲熟妇久久精品| 日韩av一国产av一中文字慕|